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Syce1
Gene Detail
 Symbol
Name
ID
Syce1
synaptonemal complex central element protein 1
MGI:1921325
Synonyms 4933406J07Rik
Feature Type protein coding gene
Genetic Map
Chromosome 7
85.96 cM, cytoband F5
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:140777229-140787854 bp, - strand
From NCBI annotation of GRCm38

  10626 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:77044  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Syce1

Human
homologs
Human Homolog SYCE1, synaptonemal complex central element protein 1
NCBI Gene ID 93426
neXtProt AC  NX_Q8N0S2
Human Synonyms  C10orf94, CT76
Human Chr (Location)  10q26.3; chr10:133553900-133568291 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit infertility associated with failure to repair double-strand breaks during meiosis leading to apoptosis of germ cell.
 
Phenotype Images(2)
Interactions
Syce1 interacts with 72 markers (Mir1a-1, Mir1a-2, Mir22, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cell cycle, cell division, ...
Component central element, chromosome, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (23)    Tissues (11)    Images (1)
Theiler Stages: 25, 28
Assay TypeResults
Immunohistochemistry 2
Western blot 4
RT-PCR 17
cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(18) cDNA(16) Primer pair(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000025480 (Evidence)
Entrez Gene74075 (Evidence)
UniGene46102
DFCITC1582631
DoTSDT.50315012
NIA Mouse Gene IndexU029432
Consensus CDS ProjectCCDS52436.1
International Mouse Knockout Project StatusSyce1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 74075 NCBI Gene Model | MGI Sequence Detail 10626 C57BL/6J ±  kb
transcript NM_001143765 RefSeq | MGI Sequence Detail 1462 C57BL/6 
polypeptide Q9D495 UniProt | EBI | MGI Sequence Detail 329 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(82 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026676 Synaptonemal complex central element protein 1
Protein Ontology PR:000015859 synaptonemal complex central element protein 1
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:208310 Fraune J, et al., Phylogenies of central element proteins reveal the dynamic evolutionary history of the mammalian synaptonemal complex: ancient and recent components. Genetics. 2013 Nov;195(3):781-93
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory