About   Help   FAQ
Asz1
Gene Detail
Symbol

Name
ID
Asz1
ankyrin repeat, SAM and basic leucine zipper domain containing 1
MGI:1921318
Synonyms
4933400N19Rik, Gasz, ORF3
Feature Type
protein coding gene
Genetic Map
Chromosome 6
8.09 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:18050964-18109061 bp, - strand
From VEGA annotation of GRCm38

  58098 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11374  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ASZ1
Gene Tree: Asz1

Human
homologs
ASZ1, ankyrin repeat, SAM and basic leucine zipper domain containing 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 136991
neXtProt AC: NX_Q8WWH4

Human Synonyms: ALP1, ANKL1, C7orf7, CT1.19, GASZ, Orf3

Human Chr (Location): 7q31.2; chr7:117363222-117427523 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Homozygous null male mice are sterile resulting from a block in spermatid development
 
Phenotype Images(1)
Interactions
Asz1 interacts with 65 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cell differentiation, DNA methylation involved in gamete generation, ...
Component cytoplasm, pi-body
Function protein binding, signal transducer activity
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (31)    Tissues (31)    Images (4)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 31
cDNA source data(11)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase asz1 ; ZFIN asz1    NEW 
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000023407 (Evidence)
Ensembl Gene Model ENSMUSG00000010796 (Evidence)
Entrez Gene 74068 (Evidence)
UniGene 73091
DFCI TC1586228
DoTS DT.91296897, DT.55218185
NIA Mouse Gene Index U027067
Consensus CDS Project CCDS19929.1
International Mouse Phenotyping Consortium Status Asz1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023407 VEGA Gene Model | MGI Sequence Detail 58098 C57BL/6J ±  kb
transcript OTTMUST00000056859 VEGA | MGI Sequence Detail 1736 Not Applicable 
polypeptide OTTMUSP00000027375 VEGA | MGI Sequence Detail 475 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(6) UniProt(2)
Polymorphisms
SNPs within 2kb(363 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002110 Ankyrin repeat
InterPro IPR020683 Ankyrin repeat-containing domain
InterPro IPR001660 Sterile alpha motif domain
InterPro IPR013761 Sterile alpha motif/pointed domain
InterPro IPR011510 Sterile alpha motif, type 2
Protein Ontology PR:000004391 ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
References
(Earliest) J:60184 Ellsworth RE, et al., Comparative genomic sequence analysis of the human and mouse cystic fibrosis transmembrane conductance regulator genes. Proc Natl Acad Sci U S A. 2000 Feb 1;97(3):1172-7
(Latest) J:204464 Lim AK, et al., The nuage mediates retrotransposon silencing in mouse primordial ovarian follicles. Development. 2013 Sep;140(18):3819-25
All references(28)
Other
accession IDs
MGI:1353469

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/21/2015
MGI 5.22
The Jackson Laboratory