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Steap2 Gene Detail
Summary
  • Symbol
    Steap2
  • Name
    six transmembrane epithelial antigen of prostate 2
  • Synonyms
    4921538B17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921301
    NCBI Gene: 74051
  • Gene Overview
    MyGene.info: STEAP2
Location & Maps
more
  • Genetic Map
    Chromosome 5, 3.18 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    STEAP2, STEAP2 metalloreductase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    STEAP2, STEAP2 metalloreductase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    IPCA1, PCANAP1, PUMPCn, STAMP1, STMP
  • Links
    NCBI Gene ID: 261729
    neXtProt AC: NX_Q8NFT2

  • Chr Location
    7q21.13; chr7:90211686-90237678 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    49
  • Gene trapped
    45
  • Targeted
    4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021588 VEGA Gene Model | MGI Sequence Detail 29750 C57BL/6J ±  kb
transcript OTTMUST00000051255 VEGA | MGI Sequence Detail 10408 Not Applicable  
polypeptide OTTMUSP00000024078 VEGA | MGI Sequence Detail 489 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    181 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000015731 metalloreductase STEAP2
  • EC
  • InterPro Domains
    IPR013130 Ferric reductase transmembrane component-like domain
    IPR016040 NAD(P)-binding domain
    IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal
Molecular
Reagents
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  • All nucleic 41
    cDNA 41

    Microarray probesets 8
Other
Accession IDs
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MGI:2141006, MGI:2141126
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory