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Steap2 Gene Detail
Summary
  • Symbol
    Steap2
  • Name
    six transmembrane epithelial antigen of prostate 2
  • Synonyms
    4921538B17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921301
    NCBI Gene: 74051
  • Gene Overview
    MyGene.info: STEAP2
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:5664829-5694568 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 3.18 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    181 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921301
protein coding gene Chr5:5664829-5694578 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029275
protein coding gene Chr5:2571979-2602249 (-)
A/J MGP_AJ_G0029238
protein coding gene Chr5:2467054-2497879 (-)
AKR/J MGP_AKRJ_G0029188
protein coding gene Chr5:2517207-2548015 (-)
BALB/cJ MGP_BALBcJ_G0029256
protein coding gene Chr5:2681714-2712090 (-)
C3H/HeJ MGP_C3HHeJ_G0028976
protein coding gene Chr5:2719497-2759007 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029706
protein coding gene Chr5:2957856-2989043 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026949
protein coding gene Chr5:2539347-2569250 (-)
CAST/EiJ MGP_CASTEiJ_G0028389
protein coding gene Chr5:2668523-2699272 (-)
CBA/J MGP_CBAJ_G0028937
protein coding gene Chr5:2946685-2983774 (-)
DBA/2J MGP_DBA2J_G0029090
protein coding gene Chr5:2617304-2650600 (-)
FVB/NJ MGP_FVBNJ_G0029051
protein coding gene Chr5:2463949-2493908 (-)
LP/J MGP_LPJ_G0029179
protein coding gene Chr5:2668330-2699137 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029078
protein coding gene Chr5:2883426-2914444 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029737
protein coding gene Chr5:2566255-2601307 (-)
PWK/PhJ MGP_PWKPhJ_G0028111
protein coding gene Chr5:2544268-2575085 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027944
protein coding gene Chr5:2861290-2891830 (-)
WSB/EiJ MGP_WSBEiJ_G0028469
protein coding gene Chr5:2606029-2637327 (-)



Homology
more
  • Human Ortholog
    STEAP2, STEAP2 metalloreductase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    STEAP2, STEAP2 metalloreductase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    IPCA1, PCANAP1, PUMPCn, STAMP1, STMP
  • Links
    NCBI Gene ID: 261729
    neXtProt AC: NX_Q8NFT2
    UniProt: Q8NFT2

  • Chr Location
    7q21.13; chr7:90211686-90243408 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74051 NCBI Gene Model | MGI Sequence Detail 29740 C57BL/6J ±  kb
transcript NM_001103157 RefSeq | MGI Sequence Detail 10696 C57BL/6  
polypeptide Q8BWB6 UniProt | EBI | MGI Sequence Detail 489 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 42
    cDNA 42

    Microarray probesets 8
Other
Accession IDs
less
MGI:2141006, MGI:2141126
References
more
  • Summaries
    All 38
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:239497 Sikkeland J, et al., STAMPing at the crossroads of normal physiology and disease states. Mol Cell Endocrinol. 2016 Apr 15;425:26-36

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory