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Ttf2 Gene Detail
Summary
  • Symbol
    Ttf2
  • Name
    transcription termination factor, RNA polymerase II
  • Synonyms
    4632434F22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921294
    NCBI Gene: 74044
  • Gene Overview
    MyGene.info: TTF2
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:100938860-100969663 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 43.86 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    272 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921294
protein coding gene Chr3:100938860-100969725 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027671
protein coding gene Chr3:102076570-102110271 (-)
A/J MGP_AJ_G0027630
protein coding gene Chr3:98860516-98891211 (-)
AKR/J MGP_AKRJ_G0027596
protein coding gene Chr3:101283108-101317176 (-)
BALB/cJ MGP_BALBcJ_G0027643
protein coding gene Chr3:98620862-98651553 (-)
C3H/HeJ MGP_C3HHeJ_G0027372
protein coding gene Chr3:101579114-101613881 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028086
protein coding gene Chr3:105822110-105860045 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025427
protein coding gene Chr3:95056033-95087833 (-)
CAST/EiJ MGP_CASTEiJ_G0026828
protein coding gene Chr3:100675755-100715053 (-)
CBA/J MGP_CBAJ_G0027347
protein coding gene Chr3:109466303-109504375 (-)
DBA/2J MGP_DBA2J_G0027490
protein coding gene Chr3:98099446-98130933 (-)
FVB/NJ MGP_FVBNJ_G0027458
protein coding gene Chr3:96033017-96064582 (-)
LP/J MGP_LPJ_G0027597
protein coding gene Chr3:103439642-103471479 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027488
protein coding gene Chr3:115691501-115724366 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028141
protein coding gene Chr3:100771652-100807069 (-)
PWK/PhJ MGP_PWKPhJ_G0026555
protein coding gene Chr3:97854910-97886197 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026377
protein coding gene Chr3:98868715-98900771 (-)
WSB/EiJ MGP_WSBEiJ_G0026908
protein coding gene Chr3:101336377-101368526 (-)



Homology
more
  • Human Ortholog
    TTF2, transcription termination factor 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TTF2, transcription termination factor 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HuF2, ZGRF6
  • Links
    NCBI Gene ID: 8458
    neXtProt AC: NX_Q9UNY4
    UniProt: Q9UNY4

  • Chr Location
    1p13.1; chr1:117060288-117107453 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033222 Ensembl Gene Model | MGI Sequence Detail 30804 C57BL/6J ±  kb
transcript ENSMUST00000076941 Ensembl | MGI Sequence Detail 4541 Not Applicable  
polypeptide ENSMUSP00000076208 Ensembl | MGI Sequence Detail 1138 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 5
Other
Accession IDs
less
MGI:2139940
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:232383 Meng T, et al., Overexpression of mouse TTF-2 gene causes cleft palate. J Cell Mol Med. 2012 Oct;16(10):2362-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory