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Pex26 Gene Detail
Summary
  • Symbol
    Pex26
  • Name
    peroxisomal biogenesis factor 26
  • Synonyms
    4632428M11Rik, peroxisome biogenesis factor 26
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921293
    NCBI Gene: 74043
  • Gene Overview
    MyGene.info: PEX26
Location & Maps
more
  • Sequence Map
    Chr6:121183667-121198837 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      15171 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 57.13 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PEX26, peroxisomal biogenesis factor 26
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PEX26, peroxisomal biogenesis factor 26
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PBD7A, PBD7B, PEX26M1T, Pex26pM1T
  • Links
    NCBI Gene ID: 55670
    neXtProt AC: NX_Q7Z412

  • Chr Location
    22q11.21; chr22:18077920-18091031 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 9922
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: PEX26
  • Gene Tree
Human Diseases
more
  • Diseases
    2 with human PEX26 associations

Human Disease Mouse Models
       Peroxisome Biogenesis Disorder 7a (zellweger); PBD7A   OMIM: 614872
Peroxisome Biogenesis Disorder 7b; PBD7B   OMIM: 614873
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    6
  • Gene trapped
    2
  • Targeted
    4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026945 VEGA Gene Model | MGI Sequence Detail 15171 C57BL/6J ±  kb
transcript OTTMUST00000066610 VEGA | MGI Sequence Detail 4093 Not Applicable  
polypeptide OTTMUSP00000033410 VEGA | MGI Sequence Detail 305 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    58 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000012563 peroxisome assembly protein 26
  • InterPro Domains
    IPR010797 Peroxisome assembly protein 26
Molecular
Reagents
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  • All nucleic 42
    cDNA 42

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141509
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory