About   Help   FAQ
Ddias Gene Detail
Summary
  • Symbol
    Ddias
  • Name
    DNA damage-induced apoptosis suppressor
  • Synonyms
    4632434I11Rik, noxin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921291
    NCBI Gene: 74041
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:92857525-92874247 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 51.64 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    277 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921291
protein coding gene Chr7:92857525-92874286 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032515
protein coding gene Chr7:95419133-95437146 (-)
A/J MGP_AJ_G0032489
protein coding gene Chr7:93036678-93053360 (-)
AKR/J MGP_AKRJ_G0032425
protein coding gene Chr7:95255859-95272545 (-)
BALB/cJ MGP_BALBcJ_G0032500
protein coding gene Chr7:92704582-92721262 (-)
C3H/HeJ MGP_C3HHeJ_G0032215
protein coding gene Chr7:95627030-95644841 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032998
protein coding gene Chr7:99099988-99116672 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029993
protein coding gene Chr7:95817108-95834899 (-)
CAST/EiJ MGP_CASTEiJ_G0031542
protein coding gene Chr7:87112478-87131982 (-)
CBA/J MGP_CBAJ_G0032182
protein coding gene Chr7:102453858-102471664 (-)
DBA/2J MGP_DBA2J_G0032334
protein coding gene Chr7:91466205-91483960 (-)
FVB/NJ MGP_FVBNJ_G0032290
protein coding gene Chr7:91303732-91321837 (-)
LP/J MGP_LPJ_G0032423
protein coding gene Chr7:96671439-96690335 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032324
protein coding gene Chr7:103572776-103598181 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033020
protein coding gene Chr7:94572316-94593300 (-)
PWK/PhJ MGP_PWKPhJ_G0031260
protein coding gene Chr7:84535936-84553846 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031103
protein coding gene Chr7:81878009-81896944 (-)
WSB/EiJ MGP_WSBEiJ_G0031659
protein coding gene Chr7:95223729-95242283 (-)



Homology
more
  • Human Ortholog
    DDIAS, DNA damage induced apoptosis suppressor
  • Vertebrate Orthologs
    8
  • Human Ortholog
    DDIAS, DNA damage induced apoptosis suppressor
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C11orf82, noxin
  • Links
    NCBI Gene ID: 220042
    neXtProt AC: NX_Q8IXT1
    UniProt: Q8IXT1

  • Chr Location
    11q14.1; chr11:82901695-82934659 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    30 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030641 Ensembl Gene Model | MGI Sequence Detail 16723 C57BL/6J ±  kb
transcript ENSMUST00000032877 Ensembl | MGI Sequence Detail 3387 Not Applicable  
polypeptide ENSMUSP00000032877 Ensembl | MGI Sequence Detail 899 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR012340 Nucleic acid-binding, OB-fold
    IPR013955 Replication factor A, C-terminal
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 3
References
more
  • Summaries
    All 49
    Gene Ontology 3
    Phenotypes 30
  • Earliest
    J:141526 Russell LB, et al., Analysis of the albino-locus region of the mouse. III. Time of death of prenatal lethals. Genetics. 1979 May;92(1):205-13
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/04/2018
MGI 6.13
The Jackson Laboratory