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Rap2b
Gene Detail
Symbol

Name
ID
Rap2b
RAP2B, member of RAS oncogene family
MGI:1921262
Synonyms
4021402C18Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 3
29.81 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:61361638-61368430 bp, + strand
From VEGA annotation of GRCm38

  6793 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55701  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RAP2B
Protein SuperFamily: ras protein
Gene Tree: Rap2b

Human
homologs
RAP2B, RAP2B, member of RAS oncogene family
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 5912
neXtProt AC: NX_P61225

Human Chr (Location): 3q25.2; chr3:153162212-153170624 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Interactions
Rap2b interacts with 281 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process negative regulation of cell migration, platelet activation, ...
Component bicellular tight junction, cell-cell contact zone, ...
Function GDP binding, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (6)    Tissues (3)    Images (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 6
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rap2b ; ZFIN rap2b    NEW 
Molecular
reagents
All nucleic(14) cDNA(14)
Microarray probesets(9)
Other database
links
VEGA Gene Model OTTMUSG00000051923 (Evidence)
Ensembl Gene Model ENSMUSG00000036894 (Evidence)
Entrez Gene 74012 (Evidence)
DFCI TC1615488, TC1578763
Consensus CDS Project CCDS17378.1
International Mouse Phenotyping Consortium Status Rap2b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051923 VEGA Gene Model | MGI Sequence Detail 6793 C57BL/6J ±  kb
transcript OTTMUST00000130706 VEGA | MGI Sequence Detail 6793 Not Applicable 
polypeptide OTTMUSP00000070018 VEGA | MGI Sequence Detail 183 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(46 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR020849 Small GTPase superfamily, Ras type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013724 ras-related protein Rap-2b
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(29)
Other
accession IDs
MGI:2139559

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory