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Rap2b
Gene Detail
 Symbol
Name
ID
Rap2b
RAP2B, member of RAS oncogene family
MGI:1921262
Synonyms 4021402C18Rik
Feature Type protein coding gene
Genetic Map
Chromosome 3
29.81 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:61364507-61368703 bp, + strand
From NCBI annotation of GRCm38

  4197 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55701  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: ras protein
Gene Tree: Rap2b

Human
homologs
Human Homolog RAP2B, RAP2B, member of RAS oncogene family
NCBI Gene ID 5912
neXtProt AC  NX_P61225
Human Chr (Location)  3q25.2; chr3:153162212-153170624 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Interactions
Rap2b interacts with 282 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process GTP catabolic process, negative regulation of cell migration, ...
Component cytosol, endosome, ...
Function GDP binding, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (6)    Tissues (3)    Images (6)
Theiler Stages: 11, 13, 23
Assay TypeResults
RNA in situ 6
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) cDNA(14)
Microarray probesets(9)
Other database
links
Ensembl Gene ModelENSMUSG00000036894 (Evidence)
Entrez Gene74012 (Evidence)
DFCITC1578763, TC1615488
Consensus CDS ProjectCCDS17378.1
International Mouse Knockout Project StatusRap2b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 74012 NCBI Gene Model | MGI Sequence Detail 4197 C57BL/6J ±  kb
transcript NM_028712 RefSeq | MGI Sequence Detail 4197 Not Specified 
polypeptide P61226 UniProt | EBI | MGI Sequence Detail 183 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(31 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR020849 Small GTPase superfamily, Ras type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013724 ras-related protein Rap-2b
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(28)
Other
accession IDs
MGI:2139559

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/02/2014
MGI 5.19
The Jackson Laboratory