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Tmco1
Gene Detail
Symbol

Name
ID
Tmco1
transmembrane and coiled-coil domains 1
MGI:1921173
Synonyms
1190006A08Rik, 4930403O06Rik, ESTM39
Feature Type
protein coding gene
Genetic Map
Chromosome 1
74.69 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:167308378-167333978 bp, + strand
From VEGA annotation of GRCm38

  25601 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10384  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: TMCO1
Protein SuperFamily: transmembrane protein
Gene Tree: Tmco1

Human
homologs
TMCO1, transmembrane and coiled-coil domains 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 54499
neXtProt AC: NX_Q9UM00

Human Synonyms: HP10122, PCIA3, PNAS-136, TMCC4

Human Chr (Location): 1q24.1; chr1:165724291-165768922 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Endonuclease-mediated(1) Gene trapped(13)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Tmco1 interacts with 343 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process biological_process
Component endoplasmic reticulum, Golgi apparatus, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (44)    Tissues (4)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 44
cDNA source data(109)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase tmco1 ; ZFIN tmco1    NEW 
Molecular
reagents
All nucleic(110) cDNA(109) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000050635 (Evidence)
Ensembl Gene Model ENSMUSG00000052428 (Evidence)
Entrez Gene 68944 (Evidence)
UniGene 330045
DFCI TC1745395, TC1653388, TC1572717
DoTS DT.101152498, DT.494633, DT.101130228, DT.101130225
NIA Mouse Gene Index U001055
Consensus CDS Project CCDS15456.1
International Mouse Phenotyping Consortium Status Tmco1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000050635 VEGA Gene Model | MGI Sequence Detail 25601 C57BL/6J ±  kb
transcript OTTMUST00000128373 VEGA | MGI Sequence Detail 1122 Not Applicable 
polypeptide OTTMUSP00000069069 VEGA | MGI Sequence Detail 200 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(3) UniProt(4)
Polymorphisms
SNPs within 2kb(135 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002809 Protein of unknown function DUF106, transmembrane
InterPro IPR008559 Uncharacterised conserved protein UCP023322, transmembrane eukaryotic
Protein Ontology PR:000029813 transmembrane and coiled-coil domain-containing protein 1
References
(Earliest) J:52606 Eddleston J, et al., Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp). Genomics. 1999 Mar 1;56(2):149-59
(Latest) J:181586 Hald J, et al., Pancreatic islet and progenitor cell surface markers with cell sorting potential. Diabetologia. 2012 Jan;55(1):154-65
All references(39)
Other
accession IDs
MGI:1334461, MGI:1916194, MGI:2138472

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory