Tmco1
Gene Detail

Symbol Name ID

Tmco1 transmembrane and coiled-coil domains 1 MGI:1921173

Synonyms

1190006A08Rik, 4930403O06Rik, ESTM39

Feature Type

protein coding gene

Genetic Map

Chromosome 1

74.69 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr1:167308670-167333978 bp, + strand From NCBI annotation of GRCm38   25309 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:10384  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: transmembrane protein
Gene Tree: Tmco1

Human homologs

Human Homolog		TMCO1, transmembrane and coiled-coil domains 1
NCBI Gene ID		54499
neXtProt AC		NX_Q9UM00
Human Synonyms		HP10122, PCIA3, PNAS-136, RP11-466F5.7, TMCC4
Human Chr (Location)		1q22-q25; chr1:165693528-165738159 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human TMCO1

Alleles and phenotypes

All alleles(13) : Gene trapped(13)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	biological_process
Component	endoplasmic reticulum, Golgi apparatus, ...
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (44)    Tissues (4)    Images (20)
Theiler Stages: 23

Assay Type	Results
RNA in situ	44

cDNA source data(109)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(110) cDNA(109) Primer pair(1)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000052428 (Evidence)
Entrez Gene	68944 (Evidence)
UniGene	330045
DFCI	TC1572717, TC1653388, TC1745395
DoTS	DT.101130225, DT.101130228, DT.101152498, DT.494633
NIA Mouse Gene Index	U001055
Consensus CDS Project	CCDS15456.1
International Mouse Knockout Project Status	Tmco1

Sequences

Length	Strain/Species
genomic	68944	NCBI Gene Model | MGI Sequence Detail	25309	C57BL/6J
transcript	NM_001039483	RefSeq | MGI Sequence Detail	4474	C57BL/6
polypeptide	Q921L3	UniProt | EBI | MGI Sequence Detail	188	Not Applicable

All sequences(32) RefSeq(3) UniProt(2)

Polymorphisms

SNPs(55 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002809	Protein of unknown function DUF106, transmembrane
InterPro	IPR008559	Uncharacterised conserved protein UCP023322, transmembrane eukaryotic
Protein Ontology	PR:000029813	transmembrane and coiled-coil domain-containing protein 1

Graphical View of Protein Domain Structure

References

(Earliest) J:52606 Eddleston J, et al., Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp). Genomics. 1999 Mar 1;56(2):149-59
(Latest) J:181586 Hald J, et al., Pancreatic islet and progenitor cell surface markers with cell sorting potential. Diabetologia. 2012 Jan;55(1):154-65
All references(37)

Other accession IDs

MGI:1334461, MGI:1916194, MGI:2138472