About   Help   FAQ
Zdbf2 Gene Detail
Summary
  • Symbol
    Zdbf2
  • Name
    zinc finger, DBF-type containing 2
  • Synonyms
    4930431J08Rik, 9330107J05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921134
    NCBI Gene: 73884
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:63312424-63353735 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 32.31 cM, cytoband C2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    360 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921134
protein coding gene Chr1:63239517-63353735 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016088
protein coding gene Chr1:63421315-63444294 (+)
A/J MGP_AJ_G0016071
protein coding gene Chr1:61175697-61219702 (+)
AKR/J MGP_AKRJ_G0016028
protein coding gene Chr1:62862393-62910295 (+)
BALB/cJ MGP_BALBcJ_G0016026
protein coding gene Chr1:61262105-61303738 (+)
C3H/HeJ MGP_C3HHeJ_G0015858
protein coding gene Chr1:63136013-63188253 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016479
protein coding gene Chr1:65861407-65909433 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014200
protein coding gene Chr1:57289560-57330443 (+)
CAST/EiJ MGP_CASTEiJ_G0015441
protein coding gene Chr1:62405934-62450807 (+)
CBA/J MGP_CBAJ_G0015830
protein coding gene Chr1:67964352-68016808 (+)
DBA/2J MGP_DBA2J_G0015931
protein coding gene Chr1:60589409-60636699 (+)
FVB/NJ MGP_FVBNJ_G0015934
protein coding gene Chr1:59884135-59925073 (+)
LP/J MGP_LPJ_G0016003
protein coding gene Chr1:64307126-64349063 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015954
protein coding gene Chr1:70881944-70939896 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016526
protein coding gene Chr1:62844766-62888386 (+)
PWK/PhJ MGP_PWKPhJ_G0015228
protein coding gene Chr1:59959188-59996107 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015007
protein coding gene Chr1:62362991-62411316 (+)
WSB/EiJ MGP_WSBEiJ_G0015503
protein coding gene Chr1:62571861-62615466 (+)



Homology
more
  • Human Ortholog
    ZDBF2, zinc finger DBF-type containing 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZDBF2, zinc finger DBF-type containing 2
  • Synonyms
    Slx9
  • Links
    NCBI Gene ID: 57683
    neXtProt AC: NX_Q9HCK1
    UniProt: Q9HCK1

  • Chr Location
    2q33.3; chr2:206274641-206314438 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a modified isoform encoding allele exhibit impaired methylation of the somatic differentially methylated region of the gene and decreased body weight and size when inherited paternally.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027520 Ensembl Gene Model | MGI Sequence Detail 41312 C57BL/6J ±  kb
    transcript ENSMUST00000239483 Ensembl | MGI Sequence Detail 12523 Not Applicable  
    polypeptide ENSMUSP00000159296 Ensembl | MGI Sequence Detail 2498 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 50
      Genomic 1
      cDNA 42
      Primer pair 7

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2442330
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 9
      Gene Ontology 2
      Phenotypes 12
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:319657 Glaser J, et al., The imprinted Zdbf2 gene finely tunes control of feeding and growth in neonates. Elife. 2022 Jan 20;11:e65641

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    07/26/2022
    MGI 6.21
    The Jackson Laboratory