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Eif3k
Gene Detail
Symbol

Name
ID
Eif3k
eukaryotic translation initiation factor 3, subunit K
MGI:1921080
Synonyms
1200009C21Rik, eIF3K, Eif3s12
Feature Type
protein coding gene
Genetic Map
Chromosome 7
16.94 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:28971373-28981814 bp, - strand
From Ensembl annotation of GRCm38

  10442 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8292  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: EIF3K
Gene Tree: Eif3k

Human
homologs
EIF3K, eukaryotic translation initiation factor 3, subunit K
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 27335
neXtProt AC: NX_Q9UBQ5

Human Synonyms: ARG134, EIF3-p28, EIF3S12, HSPC029, M9, MSTP001, PLAC24, PLAC-24, PRO1474, PTD001

Human Chr (Location): 19q13.2; chr19:38618419-38636959 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(77) : Gene trapped(75) Targeted(2)
Incidental mutations (data from APF , CvDC )
Interactions
Eif3k interacts with 5 markers (Mir455, Mir702, Mir1952, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process regulation of translational initiation, translation, ...
Component cytoplasm, eukaryotic translation initiation factor 3 complex, ...
Function ribosome binding, RNA binding, ...
External Resources: FuncBase
Expression
cDNA source data(183)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase eif3k    NEW 
Molecular
reagents
All nucleic(183) cDNA(183)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000053565 (Evidence)
Entrez Gene 73830 (Evidence)
UniGene 29714
DFCI TC1625991, TC1591674, TC1574351
DoTS DT.99850035, DT.101287470
NIA Mouse Gene Index U110977
Consensus CDS Project CCDS21062.1
International Mouse Phenotyping Consortium Status Eif3k
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053565 Ensembl Gene Model | MGI Sequence Detail 10442 C57BL/6J ±  kb
transcript ENSMUST00000066070 Ensembl | MGI Sequence Detail 773 Not Applicable 
polypeptide ENSMUSP00000066038 Ensembl | MGI Sequence Detail 218 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(8) UniProt(2)
Polymorphisms
SNPs within 2kb(73 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
InterPro IPR009374 Eukaryotic translation initiation factor 3 subunit K
InterPro IPR005062 SAC3/GANP/Nin1/mts3/eIF-3 p25
InterPro IPR016020 Translation initiation factor 3, subunit 12, N-terminal, eukaryotic
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
Protein Ontology PR:000006983 eukaryotic translation initiation factor 3 subunit K
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory