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Eif3k Gene Detail
Summary
  • Symbol
    Eif3k
  • Name
    eukaryotic translation initiation factor 3, subunit K
  • Synonyms
    1200009C21Rik, eIF3K, Eif3s12
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921080
    NCBI Gene: 73830
  • Gene Overview
    MyGene.info: EIF3K
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:28971372-28981864 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 16.94 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    74 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921080
protein coding gene Chr7:28971372-28981888 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031968
protein coding gene Chr7:27858231-27869835 (-)
A/J MGP_AJ_G0031946
protein coding gene Chr7:27129263-27139666 (-)
AKR/J MGP_AKRJ_G0031878
protein coding gene Chr7:27830748-27840936 (-)
BALB/cJ MGP_BALBcJ_G0031953
protein coding gene Chr7:27282450-27292848 (-)
C3H/HeJ MGP_C3HHeJ_G0031672
protein coding gene Chr7:28234162-28244110 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032417
protein coding gene Chr7:28741282-28754001 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029469
protein coding gene Chr7:28189327-28200042 (-)
CAST/EiJ MGP_CASTEiJ_G0031007
protein coding gene Chr7:21526234-21537777 (-)
CBA/J MGP_CBAJ_G0031638
protein coding gene Chr7:30097288-30107236 (-)
DBA/2J MGP_DBA2J_G0031790
protein coding gene Chr7:26874834-26885028 (-)
FVB/NJ MGP_FVBNJ_G0031747
protein coding gene Chr7:26964377-26974456 (-)
LP/J MGP_LPJ_G0031870
protein coding gene Chr7:28155686-28169307 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031783
protein coding gene Chr7:29479414-29493130 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032447
protein coding gene Chr7:27314527-27324922 (-)
PWK/PhJ MGP_PWKPhJ_G0030732
protein coding gene Chr7:21912642-21922911 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030565
protein coding gene Chr7:18333400-18348709 (-)
WSB/EiJ MGP_WSBEiJ_G0031116
protein coding gene Chr7:27688939-27699712 (-)



Homology
more
  • Human Ortholog
    EIF3K, eukaryotic translation initiation factor 3 subunit K
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EIF3K, eukaryotic translation initiation factor 3 subunit K
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARG134, EIF3-p28, EIF3S12, HSPC029, M9, MSTP001, PLAC24, PLAC-24, PRO1474, PTD001
  • Links
    NCBI Gene ID: 27335
    neXtProt AC: NX_Q9UBQ5
    UniProt: Q9UBQ5

  • Chr Location
    19q13.2; chr19:38619072-38636959 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8292
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: EIF3K
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053565 Ensembl Gene Model | MGI Sequence Detail 10493 C57BL/6J ±  kb
transcript ENSMUST00000066070 Ensembl | MGI Sequence Detail 774 Not Applicable  
polypeptide ENSMUSP00000066038 Ensembl | MGI Sequence Detail 218 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000006983 eukaryotic translation initiation factor 3 subunit K
  • InterPro Domains
    IPR016024 Armadillo-type fold
    IPR033464 CSN8/PSMD8/EIF3K
    IPR009374 Eukaryotic translation initiation factor 3 subunit K
    IPR000717 Proteasome component (PCI) domain
    IPR016020 Translation initiation factor 3, subunit 12, N-terminal, eukaryotic
    IPR036390 Winged helix DNA-binding domain superfamily
    IPR036388 Winged helix-like DNA-binding domain superfamily
Molecular
Reagents
less
  • All nucleic 184
    cDNA 184

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Gene Ontology 7
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory