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Dcaf4 Gene Detail
Summary
  • Symbol
    Dcaf4
  • Name
    DDB1 and CUL4 associated factor 4
  • Synonyms
    1110018E21Rik, Wdr21
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921078
    NCBI Gene: 73828
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:83520466-83541920 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 38.75 cM, cytoband D3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    157 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921078
protein coding gene Chr12:83520456-83541994 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019913
protein coding gene Chr12:84158319-84182640 (+)
A/J MGP_AJ_G0019870
protein coding gene Chr12:80971612-80993671 (+)
AKR/J MGP_AKRJ_G0019846
protein coding gene Chr12:83161631-83183022 (+)
BALB/cJ MGP_BALBcJ_G0019850
protein coding gene Chr12:81322371-81345186 (+)
C3H/HeJ MGP_C3HHeJ_G0019656
protein coding gene Chr12:83630432-83652910 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020302
protein coding gene Chr12:86557043-86581555 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017919
protein coding gene Chr12:77899948-77921876 (+)
CAST/EiJ MGP_CASTEiJ_G0019205
protein coding gene Chr12:78567879-78591852 (+)
CBA/J MGP_CBAJ_G0019627
protein coding gene Chr12:89899040-89926591 (+)
DBA/2J MGP_DBA2J_G0019742
protein coding gene Chr12:80523435-80544527 (+)
FVB/NJ MGP_FVBNJ_G0019728
protein coding gene Chr12:79464368-79486842 (+)
LP/J MGP_LPJ_G0019814
protein coding gene Chr12:84032772-84055814 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019767
protein coding gene Chr12:92870026-92896287 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020336
protein coding gene Chr12:82757730-82780644 (+)
PWK/PhJ MGP_PWKPhJ_G0018969
protein coding gene Chr12:74996106-75019094 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018764
protein coding gene Chr12:77219408-77242189 (+)
WSB/EiJ MGP_WSBEiJ_G0019257
protein coding gene Chr12:83418047-83444777 (+)



Homology
more
  • Human Ortholog
    DCAF4, DDB1 and CUL4 associated factor 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DCAF4, DDB1 and CUL4 associated factor 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    WDR21, WDR21A
  • Links
    NCBI Gene ID: 26094
    neXtProt AC: NX_Q8WV16
    UniProt: Q8WV16

  • Chr Location
    14q24.2; chr14:72926332-72962098 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9210
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DCAF4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021222 Ensembl Gene Model | MGI Sequence Detail 21455 C57BL/6J ±  kb
transcript ENSMUST00000223291 Ensembl | MGI Sequence Detail 2005 Not Applicable  
polypeptide ENSMUSP00000152717 Ensembl | MGI Sequence Detail 532 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR001680 WD40 repeat
    IPR017986 WD40-repeat-containing domain
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 77
    cDNA 77

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory