About   Help   FAQ
Dcaf4 Gene Detail
Summary
  • Symbol
    Dcaf4
  • Name
    DDB1 and CUL4 associated factor 4
  • Synonyms
    1110018E21Rik, Wdr21
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921078
    NCBI Gene: 73828
Location & Maps
more
  • Sequence Map
    Chr12:83520466-83541988 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      21523 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 38.75 cM, cytoband D3
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DCAF4, DDB1 and CUL4 associated factor 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DCAF4, DDB1 and CUL4 associated factor 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    WDR21, WDR21A
  • Links
    NCBI Gene ID: 26094
    neXtProt AC: NX_Q8WV16
    UniProt: Q8WV16

  • Chr Location
    14q24.2; chr14:72926332-72962098 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9210
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DCAF4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021222 Ensembl Gene Model | MGI Sequence Detail 21523 C57BL/6J ±  kb
transcript ENSMUST00000021645 Ensembl | MGI Sequence Detail 2081 Not Applicable  
polypeptide ENSMUSP00000021645 Ensembl | MGI Sequence Detail 519 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    159 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001680 WD40 repeat
    IPR017986 WD40-repeat-containing domain
    IPR015943 WD40/YVTN repeat-like-containing domain
Molecular
Reagents
less
  • All nucleic 76
    cDNA 76

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/14/2017
MGI 6.08
The Jackson Laboratory