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Wdr70 Gene Detail
Summary
  • Symbol
    Wdr70
  • Name
    WD repeat domain 70
  • Synonyms
    4833422F06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921020
    NCBI Gene: 545085
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:7873055-8099209 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 3.82 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    844 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921020
protein coding gene Chr15:7873055-8099209 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021703
protein coding gene Chr15:4900756-5136501 (-)
A/J MGP_AJ_G0021664
protein coding gene Chr15:4783872-5013010 (-)
AKR/J MGP_AKRJ_G0021642
protein coding gene Chr15:4816818-5044064 (-)
BALB/cJ MGP_BALBcJ_G0021671
protein coding gene Chr15:4687899-4922239 (-)
C3H/HeJ MGP_C3HHeJ_G0021447
protein coding gene Chr15:4851590-5094385 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022110
protein coding gene Chr15:5081522-5328415 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019647
protein coding gene Chr15:4385570-4589700 (-)
CAST/EiJ MGP_CASTEiJ_G0020963
protein coding gene Chr15:4843707-5066097 (-)
CBA/J MGP_CBAJ_G0021416
protein coding gene Chr15:5182123-5451855 (-)
DBA/2J MGP_DBA2J_G0021540
protein coding gene Chr15:4711268-4934387 (-)
FVB/NJ MGP_FVBNJ_G0021518
protein coding gene Chr15:4623916-4854817 (-)
LP/J MGP_LPJ_G0021608
protein coding gene Chr15:4832354-5065629 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021543
protein coding gene Chr15:5396055-5668447 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022133
protein coding gene Chr15:4863167-5086008 (-)
PWK/PhJ MGP_PWKPhJ_G0020706
protein coding gene Chr15:4718289-4934091 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020544
protein coding gene Chr15:4744590-4965009 (-)
WSB/EiJ MGP_WSBEiJ_G0021019
protein coding gene Chr15:4784393-5031713 (-)



Homology
more
  • Human Ortholog
    WDR70, WD repeat domain 70
  • Vertebrate Orthologs
    10
  • Human Ortholog
    WDR70, WD repeat domain 70
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 55100
    neXtProt AC: NX_Q9NW82
    UniProt: Q9NW82

  • Chr Location
    5p13.2; chr5:37379280-37752672 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9972
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: WDR70
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 545085 NCBI Gene Model | MGI Sequence Detail 226155 C57BL/6J ±  kb
transcript NM_001081402 RefSeq | MGI Sequence Detail 2151 C57BL/6  
polypeptide Q3TWF6 UniProt | EBI | MGI Sequence Detail 657 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 53
    cDNA 53

    Microarray probesets 4
References
more
  • Summaries
    All 27
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/01/2019
MGI 6.14
The Jackson Laboratory