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Gins2 Gene Detail
Summary
  • Symbol
    Gins2
  • Name
    GINS complex subunit 2 (Psf2 homolog)
  • Synonyms
    2210013I18Rik, 4833427B12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921019
    NCBI Gene: 272551
  • Gene Overview
    MyGene.info: GINS2
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:120581266-120589075 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 69.86 cM, cytoband E1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    64 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921019
protein coding gene Chr8:120578633-120589304 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034201
protein coding gene Chr8:124011012-124021517 (-)
A/J MGP_AJ_G0034181
protein coding gene Chr8:118860908-118872597 (-)
AKR/J MGP_AKRJ_G0034108
protein coding gene Chr8:122310769-122336761 (-)
BALB/cJ MGP_BALBcJ_G0034175
protein coding gene Chr8:119076295-119087316 (-)
C3H/HeJ MGP_C3HHeJ_G0033886
protein coding gene Chr8:123052229-123063456 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034695
protein coding gene Chr8:128133334-128147060 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031637
protein coding gene Chr8:111737189-111747435 (-)
CAST/EiJ MGP_CASTEiJ_G0033213
protein coding gene Chr8:123049029-123061710 (-)
CBA/J MGP_CBAJ_G0033859
protein coding gene Chr8:132820018-132833430 (-)
DBA/2J MGP_DBA2J_G0034015
protein coding gene Chr8:118079979-118090672 (-)
FVB/NJ MGP_FVBNJ_G0033958
protein coding gene Chr8:117152652-117163940 (-)
LP/J MGP_LPJ_G0034104
protein coding gene Chr8:124131639-124142154 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034005
protein coding gene Chr8:135186481-135197094 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034713
protein coding gene Chr8:122485861-122498877 (-)
PWK/PhJ MGP_PWKPhJ_G0032915
protein coding gene Chr8:117857672-117868751 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032755
protein coding gene Chr8:121188238-121200792 (-)
WSB/EiJ MGP_WSBEiJ_G0033329
protein coding gene Chr8:123224024-123234170 (-)



Homology
more
  • Human Ortholog
    GINS2, GINS complex subunit 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GINS2, GINS complex subunit 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HSPC037, Pfs2, PSF2
  • Links
    NCBI Gene ID: 51659
    neXtProt AC: NX_Q9Y248
    UniProt: Q9Y248

  • Chr Location
    16q24.1; chr16:85677674-85688982 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 272551 NCBI Gene Model | MGI Sequence Detail 7810 C57BL/6J ±  kb
transcript NM_178856 RefSeq | MGI Sequence Detail 1061 C57BL/6  
polypeptide Q9D600 UniProt | EBI | MGI Sequence Detail 185 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 5
Other
Accession IDs
less
MGI:1922932, MGI:2142506
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:187480 Westendorp B, et al., The E2F6 repressor activates gene expression in myocardium resulting in dilated cardiomyopathy. FASEB J. 2012 Jun;26(6):2569-79

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory