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Thap1
Gene Detail
Symbol

Name
ID
Thap1
THAP domain containing, apoptosis associated protein 1
MGI:1921004
Synonyms
4833431A01Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 8
14.40 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:26158212-26162940 bp, + strand
From VEGA annotation of GRCm38

  4729 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10005  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: THAP1
Gene Tree: Thap1

Human
homologs
THAP1, THAP domain containing, apoptosis associated protein 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 55145
neXtProt AC: NX_Q9NVV9

Human Synonyms: DYT6

Human Chr (Location): 8p11.21; chr8:42836674-42843331 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human THAP1

Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(14)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Thap1 interacts with 64 markers (Mir16-1, Mir29a, Mir32, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell cycle, endothelial cell proliferation, ...
Component nucleus
Function DNA binding, identical protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (52)    Tissues (31)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 52
cDNA source data(25)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase thap1    NEW 
Molecular
reagents
All nucleic(25) cDNA(25)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000031061 (Evidence)
Ensembl Gene Model ENSMUSG00000037214 (Evidence)
Entrez Gene 73754 (Evidence)
UniGene 383241
DFCI TC1582842, TC1673062
DoTS DT.110874365, DT.99856590, DT.94185102
NIA Mouse Gene Index U042895
Consensus CDS Project CCDS22208.1
International Mouse Phenotyping Consortium Status Thap1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031061 VEGA Gene Model | MGI Sequence Detail 4729 C57BL/6J ±  kb
transcript OTTMUST00000076951 VEGA | MGI Sequence Detail 1013 Not Applicable 
polypeptide OTTMUSP00000040574 VEGA | MGI Sequence Detail 210 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(8 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026516 THAP domain-containing protein 1
InterPro IPR006612 Zinc finger, C2CH-type
Protein Ontology PR:000016303 THAP domain-containing protein 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:152068 Friedel RH, et al., EUCOMM--the European conditional mouse mutagenesis program. Brief Funct Genomic Proteomic. 2007 Sep;6(3):180-5
All references(30)
Other
accession IDs
MGI:2142789

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory