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Thap1
Gene Detail
 Symbol
Name
ID
Thap1
THAP domain containing, apoptosis associated protein 1
MGI:1921004
Synonyms 4833431A01Rik
Feature Type protein coding gene
Genetic Map
Chromosome 8
14.40 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:26158212-26162940 bp, + strand
From VEGA annotation of GRCm38

  4729 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10005  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Thap1

Human
homologs
Human Homolog THAP1, THAP domain containing, apoptosis associated protein 1
NCBI Gene ID 55145
neXtProt AC  NX_Q9NVV9
Human Synonyms  DYT6
Human Chr (Location)  8p11.21; chr8:42836674-42843331 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human THAP1
Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(14)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Thap1 interacts with 64 markers (Mir16-1, Mir29a, Mir32, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cell cycle, endothelial cell proliferation, ...
Component nucleus
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (52)    Tissues (31)    Images (5)
Theiler Stages: 17, 21, 23
Assay TypeResults
RNA in situ 52
cDNA source data(25)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(25) cDNA(25)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000031061 (Evidence)
Ensembl Gene ModelENSMUSG00000037214 (Evidence)
Entrez Gene73754 (Evidence)
UniGene383241
DFCITC1582842, TC1673062
DoTSDT.110874365, DT.94185102, DT.99856590
NIA Mouse Gene IndexU042895
Consensus CDS ProjectCCDS22208.1
International Mouse Knockout Project StatusThap1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031061 VEGA Gene Model | MGI Sequence Detail 4729 C57BL/6J ±  kb
transcript OTTMUST00000076951 VEGA | MGI Sequence Detail 1013 Not Applicable 
polypeptide OTTMUSP00000040574 VEGA | MGI Sequence Detail 210 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(6) UniProt(2)
Polymorphisms SNPs within 2kb(8 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026516 THAP domain-containing protein 1
InterPro IPR006612 Zinc finger, C2CH-type
Protein Ontology PR:000016303 THAP domain-containing protein 1
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:152068 Friedel RH, et al., EUCOMM--the European conditional mouse mutagenesis program. Brief Funct Genomic Proteomic. 2007 Sep;6(3):180-5
All references(32)
Other
accession IDs
MGI:2142789

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory