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Mcmbp Gene Detail
Summary
  • Symbol
    Mcmbp
  • Name
    minichromosome maintenance complex binding protein
  • Synonyms
    1110007A13Rik, MGC:36596
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920977
    NCBI Gene: 210711
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:128696441-128740429 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 70.41 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    289 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920977
protein coding gene Chr7:128696441-128740495 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033086
protein coding gene Chr7:133133609-133176887 (-)
A/J MGP_AJ_G0033068
protein coding gene Chr7:129561386-129606876 (-)
AKR/J MGP_AKRJ_G0033000
protein coding gene Chr7:132952309-132997862 (-)
BALB/cJ MGP_BALBcJ_G0033069
protein coding gene Chr7:129215421-129261289 (-)
C3H/HeJ MGP_C3HHeJ_G0032783
protein coding gene Chr7:132831517-132876944 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033579
protein coding gene Chr7:138317447-138366177 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030551
protein coding gene Chr7:130723433-130765351 (-)
CAST/EiJ MGP_CASTEiJ_G0032113
protein coding gene Chr7:124626628-124671579 (-)
CBA/J MGP_CBAJ_G0032756
protein coding gene Chr7:143069607-143116657 (-)
DBA/2J MGP_DBA2J_G0032908
protein coding gene Chr7:127537255-127581625 (-)
FVB/NJ MGP_FVBNJ_G0032861
protein coding gene Chr7:127401863-127445867 (-)
LP/J MGP_LPJ_G0033002
protein coding gene Chr7:134607154-134650451 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032893
protein coding gene Chr7:144075222-144123808 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033598
protein coding gene Chr7:131908647-131953483 (-)
PWK/PhJ MGP_PWKPhJ_G0031819
protein coding gene Chr7:120555347-120599197 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031665
protein coding gene Chr7:118718405-118762949 (-)
WSB/EiJ MGP_WSBEiJ_G0032224
protein coding gene Chr7:132887779-132936153 (-)



Homology
more
  • Human Ortholog
    MCMBP, minichromosome maintenance complex binding protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MCMBP, minichromosome maintenance complex binding protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C10orf119, MCM-BP
  • Links
    NCBI Gene ID: 79892
    neXtProt AC: NX_Q9BTE3
    UniProt: Q9BTE3

  • Chr Location
    10q26.11; chr10:119829404-119873628 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11749
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MCMBP
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 210711 NCBI Gene Model | MGI Sequence Detail 43989 C57BL/6J ±  kb
transcript NM_145955 RefSeq | MGI Sequence Detail 4171 C57BL/6  
polypeptide Q8R3C0 UniProt | EBI | MGI Sequence Detail 642 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR019140 Mini-chromosome maintenance complex-binding protein
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 6
Other
Accession IDs
less
MGI:2142122, MGI:2384809
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory