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Sh3bgrl3
Gene Detail
 Symbol
Name
ID
Sh3bgrl3
SH3 domain binding glutamic acid-rich protein-like 3
MGI:1920973
Synonyms 1110004L05Rik
Feature Type protein coding gene
Genetic Map
Chromosome 4
66.50 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:134127406-134128789 bp, - strand
From VEGA annotation of GRCm38

  1384 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41824  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Sh3bgrl3

Human
homologs
Human Homolog SH3BGRL3, SH3 domain binding glutamate-rich protein like 3
NCBI Gene ID 83442
neXtProt AC  NX_Q9H299
Human Synonyms  HEL-S-297, SH3BP-1, TIP-B1
Human Chr (Location)  1p36.11; chr1:26279722-26281522 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(4) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sh3bgrl3 interacts with 37 markers (Mir1a-1, Mir1a-2, Mir27a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cell redox homeostasis, positive regulation of Rho GTPase activity, ...
Component cytoplasm, extracellular vesicular exosome, ...
Function electron carrier activity, protein disulfide oxidoreductase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (59)    Tissues (9)    Images (21)
Theiler Stages: 23
Assay TypeResults
RNA in situ 59
cDNA source data(6)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000010335 (Evidence)
Ensembl Gene ModelENSMUSG00000028843 (Evidence)
Entrez Gene73723 (Evidence)
DFCITC1574852
NIA Mouse Gene IndexU025632
PDB1J0F, 1T1V
Consensus CDS ProjectCCDS38910.1
International Mouse Knockout Project StatusSh3bgrl3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010335 VEGA Gene Model | MGI Sequence Detail 1384 C57BL/6J ±  kb
transcript OTTMUST00000024051 VEGA | MGI Sequence Detail 743 Not Applicable 
polypeptide OTTMUSP00000011036 VEGA | MGI Sequence Detail 93 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(35 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002109 Glutaredoxin
InterPro IPR006993 SH3-binding, glutamic acid-rich protein
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000014817 SH3 domain-binding glutamic acid-rich-like protein 3
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)
Other
accession IDs
MGI:2140464

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory