About   Help   FAQ
Sh3bgrl3 Gene Detail
Summary
  • Symbol
    Sh3bgrl3
  • Name
    SH3 domain binding glutamic acid-rich protein-like 3
  • Synonyms
    1110004L05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920973
    NCBI Gene: 73723
  • Gene Overview
    MyGene.info: SH3BGRL3
Location & Maps
more
  • Sequence Map
    Chr4:134127406-134128789 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1384 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 66.50 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SH3BGRL3, SH3 domain binding glutamate rich protein like 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SH3BGRL3, SH3 domain binding glutamate rich protein like 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HEL-S-297, SH3BP-1, TIP-B1
  • Links
    NCBI Gene ID: 83442
    neXtProt AC: NX_Q9H299

  • Chr Location
    1p36.11; chr1:26279722-26281522 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    2
  • Gene trapped
    4
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    4 involving Sh3bgrl3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010335 VEGA Gene Model | MGI Sequence Detail 1384 C57BL/6J ±  kb
transcript OTTMUST00000024051 VEGA | MGI Sequence Detail 743 Not Applicable  
polypeptide OTTMUSP00000011036 VEGA | MGI Sequence Detail 93 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    34 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000014817 SH3 domain-binding glutamic acid-rich-like protein 3
  • PDB
  • InterPro Domains
    IPR002109 Glutaredoxin
    IPR006993 SH3-binding, glutamic acid-rich protein
    IPR012336 Thioredoxin-like fold
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140464
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/27/2016
MGI 6.05
The Jackson Laboratory