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Spmip6 Gene Detail
Summary
  • Symbol
    Spmip6
  • Name
    sperm microtubule inner protein 6
  • Synonyms
    1110017D15Rik, Cbe1, Smrp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920971
    NCBI Gene: 73721
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:41505009-41517333 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 21.70 cM, cytoband B1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    370 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920971
 protein coding gene Chr4:41505005-41517333 (-)
129S1/SvImJ ENSMUSG00200004187
 protein coding gene Chr4:38352348-38364752 (-)
A/J ENSMUSG00195002803
 protein coding gene Chr4:38722906-38735527 (-)
AKR/J ENSMUSG00220029955
 protein coding gene Chr4:38551552-38564179 (-)
BALB/cJ ENSMUSG00180023665
 protein coding gene Chr4:38309709-38322332 (-)
C3H/HeJ ENSMUSG00175021826
 protein coding gene Chr4:38688403-38700864 (-)
C57BL/6NJ ENSMUSG00215027590
 protein coding gene Chr4:38326139-38338471 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025915
 protein coding gene Chr4:35606403-35618800 (-)
CAST/EiJ ENSTCUG00005003762
 protein coding gene Chr4:38186225-38198567 (-)
CBA/J ENSMUSG00210006805
 protein coding gene Chr4:38389318-38401779 (-)
DBA/2J ENSMUSG00185006114
 protein coding gene Chr4:38463095-38475554 (-)
FVB/NJ ENSMUSG00205016239
 protein coding gene Chr4:38013911-38026372 (-)
JF1/MsJ ENSUMUG00000013243
 protein coding gene Chr4:38407232-38419510 (-)
LP/J ENSMUSG00230042428
 protein coding gene Chr4:41845890-41858375 (-)
NOD/ShiLtJ ENSMUSG00190005247
 protein coding gene Chr4:38412787-38425411 (-)
NZO/HlLtJ ENSMUSG00225006552
 protein coding gene Chr4:45721801-45734425 (-)
PWK/PhJ ENSLUMG00010006099
 protein coding gene Chr4:37962940-37975367 (-)
SPRET/EiJ ENSMSPG00010023253
 protein coding gene Chr4:38907362-38919974 (-)
WSB/EiJ ENSIUOG00005047940
 protein coding gene Chr4:38268764-38281223 (-)



Homology
more
  • Human Ortholog
    SPMIP6, sperm microtubule inner protein 6
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPMIP6, sperm microtubule inner protein 6
  • Synonyms
    bA573M23.4, C9orf24, CBE1, NYD-SP22, SMRP1
  • Links
    NCBI Gene ID: 84688
    UniProt: Q8NCR6

  • Chr Location
    9p13.3; chr9:34379019-34397828 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    817
  • Tissues
    43
  • cDNA Data
    27
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028441 Ensembl Gene Model | MGI Sequence Detail 12325 C57BL/6J ±  kb
transcript ENSMUST00000030152 Ensembl | MGI Sequence Detail 1114 Not Applicable  
polypeptide ENSMUSP00000030152 Ensembl | MGI Sequence Detail 260 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 36
    cDNA 27
    Primer pair 9

    Microarray probesets 3
Other
Accession IDs
less
MGI:7470727
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory