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Rbm20
Gene Detail
 Symbol
Name
ID
Rbm20
RNA binding motif protein 20
MGI:1920963
Synonyms 1110018J23Rik, 2010003H22Rik
Feature Type protein coding gene
Genetic Map
Chromosome 19
48.28 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:53677306-53867080 bp, + strand
From VEGA annotation of GRCm38

  189775 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:28386  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Rbm20

Human
homologs
Human Homolog RBM20, RNA binding motif protein 20
NCBI Gene ID 282996
neXtProt AC  NX_Q5T481
Human Chr (Location)  10q25.2; chr10:110644397-110839469 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human RBM20
Alleles
and
phenotypes
All alleles(11) : Gene trapped(9) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for an allele lacking the RNA recognition motif exhibit increased titin compliance, and attenuated Frank-Starling mechanism.
 
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process heart development, mRNA processing, ...
Component nucleus
Function nucleic acid binding, nucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (106)    Tissues (11)    Images (20)
Theiler Stages: 23
Assay TypeResults
RNA in situ 106
cDNA source data(21)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(21) cDNA(21)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000033320 (Evidence)
Ensembl Gene ModelENSMUSG00000043639 (Evidence)
Entrez Gene73713 (Evidence)
UniGene313695
DFCITC1607841, TC1631269, TC1643839, TC1658060
DoTSDT.101125793, DT.485144
Consensus CDS ProjectCCDS50468.1
International Mouse Knockout Project StatusRbm20
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033320 VEGA Gene Model | MGI Sequence Detail 189775 C57BL/6J ±  kb
transcript OTTMUST00000083603 VEGA | MGI Sequence Detail 2529 Not Applicable 
polypeptide OTTMUSP00000044954 VEGA | MGI Sequence Detail 809 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(5) UniProt(3)
Polymorphisms SNPs within 2kb(1413 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR000690 Zinc finger, C2H2-type matrin
InterPro IPR003604 Zinc finger, U1-type
Protein Ontology PR:000031033 probable RNA-binding protein 20
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:208676 Methawasin M, et al., Experimentally increasing titin compliance in a novel mouse model attenuates the frank-starling mechanism but has a beneficial effect on diastole. Circulation. 2014 May 13;129(19):1924-36
All references(35)
Other
accession IDs
MGI:1917122, MGI:2147587

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory