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Ppp2r1b
Gene Detail
 Symbol
Name
ID
Ppp2r1b
protein phosphatase 2, regulatory subunit A, beta
MGI:1920949
Synonyms 2410091N08Rik
Feature Type protein coding gene
Genetic Map
Chromosome 9
27.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:50845301-50894229 bp, + strand
From VEGA annotation of GRCm38

  48929 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:70244  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: serine/threonine-protein phosphataser PP2A regulatory subunit A
Gene Tree: Ppp2r1b

Human
homologs
Human Homolog PPP2R1B, protein phosphatase 2, regulatory subunit A, beta
NCBI Gene ID 5519
neXtProt AC  NX_P30154
Human Synonyms  PP2A-Abeta, PR65B
Human Chr (Location)  11q23.2; chr11:111725304-111769101 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human PPP2R1B
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ppp2r1b interacts with 359 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process apoptotic process involved in morphogenesis, positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
Component membrane raft
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (81)    Tissues (31)    Images (23)
Theiler Stages: 23, 28
Assay TypeResults
Immunohistochemistry 5
RNA in situ 64
Western blot 4
RT-PCR 8
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) cDNA(12) Primer pair(2)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000037681 (Evidence)
Ensembl Gene ModelENSMUSG00000032058 (Evidence)
Entrez Gene73699 (Evidence)
NIA Mouse Gene IndexU010472
Consensus CDS ProjectCCDS40625.1, CCDS40626.1, CCDS72232.1
International Mouse Knockout Project StatusPpp2r1b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037681 VEGA Gene Model | MGI Sequence Detail 48929 C57BL/6J ±  kb
transcript OTTMUST00000097364 VEGA | MGI Sequence Detail 2195 Not Applicable 
polypeptide OTTMUSP00000054606 VEGA | MGI Sequence Detail 694 Not Applicable 

For the selected sequences
All sequences(85) RefSeq(13) UniProt(10)
Polymorphisms SNPs within 2kb(308 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011989 Armadillo-like helical
InterPro IPR016024 Armadillo-type fold
InterPro IPR000357 HEAT
InterPro IPR021133 HEAT, type 2
Protein Ontology PR:000013135 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)
Other
accession IDs
MGI:2143121

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory