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Ppp2r1b
Gene Detail
Symbol

Name
ID
Ppp2r1b
protein phosphatase 2, regulatory subunit A, beta
MGI:1920949
Synonyms
2410091N08Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 9
27.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:50845301-50894229 bp, + strand
From VEGA annotation of GRCm38

  48929 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:70244  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PPP2R1B
Protein SuperFamily: serine/threonine-protein phosphataser PP2A regulatory subunit A
Gene Tree: Ppp2r1b

Human
homologs
PPP2R1B, protein phosphatase 2, regulatory subunit A, beta
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 5519
neXtProt AC: NX_P30154

Human Synonyms: PP2A-Abeta, PR65B

Human Chr (Location): 11q23.2; chr11:111695074-111766445 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human PPP2R1B

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Ppp2r1b interacts with 358 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (81)    Tissues (31)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 5
RNA in situ 64
Western blot 4
RT-PCR 8
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase pdgfb ; ZFIN ppp2r1b    NEW 
Molecular
reagents
All nucleic(14) cDNA(12) Primer pair(2)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000037681 (Evidence)
Ensembl Gene Model ENSMUSG00000032058 (Evidence)
Entrez Gene 73699 (Evidence)
NIA Mouse Gene Index U010472
Consensus CDS Project CCDS40625.1, CCDS40626.1, CCDS72232.1
International Mouse Phenotyping Consortium Status Ppp2r1b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037681 VEGA Gene Model | MGI Sequence Detail 48929 C57BL/6J ±  kb
transcript OTTMUST00000097364 VEGA | MGI Sequence Detail 2195 Not Applicable 
polypeptide OTTMUSP00000054606 VEGA | MGI Sequence Detail 694 Not Applicable 

For the selected sequences
All sequences(86) RefSeq(14) UniProt(10)
Polymorphisms
SNPs within 2kb(308 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011989 Armadillo-like helical
InterPro IPR016024 Armadillo-type fold
InterPro IPR000357 HEAT
InterPro IPR021133 HEAT, type 2
Protein Ontology PR:000013135 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)
Other
accession IDs
MGI:2143121

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory