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Tex19.1 Gene Detail
Summary
  • Symbol
    Tex19.1
  • Name
    testis expressed gene 19.1
  • Synonyms
    2410081M02Rik, Tex19, Tex19.1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920929
    NCBI Gene: 73679
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:121146143-121148314 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 85.00 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    25 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920929
protein coding gene Chr11:121146143-121148319 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019539
protein coding gene Chr11:125680200-125682376 (+)
A/J MGP_AJ_G0019506
protein coding gene Chr11:120069389-120071565 (+)
AKR/J MGP_AKRJ_G0019476
protein coding gene Chr11:123705451-123707627 (+)
BALB/cJ MGP_BALBcJ_G0019481
protein coding gene Chr11:120435949-120438125 (+)
C3H/HeJ MGP_C3HHeJ_G0019287
protein coding gene Chr11:124028915-124031091 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019930
protein coding gene Chr11:129494560-129496736 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017555
protein coding gene Chr11:117047566-117049739 (+)
CAST/EiJ MGP_CASTEiJ_G0018841
protein coding gene Chr11:125529898-125532071 (+)
CBA/J MGP_CBAJ_G0019258
protein coding gene Chr11:134528933-134531109 (+)
DBA/2J MGP_DBA2J_G0019371
protein coding gene Chr11:119435073-119437249 (+)
FVB/NJ MGP_FVBNJ_G0019362
protein coding gene Chr11:119151784-119153959 (+)
LP/J MGP_LPJ_G0019442
protein coding gene Chr11:125959556-125961732 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019395
protein coding gene Chr11:133342003-133344179 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019969
protein coding gene Chr11:124380481-124382657 (+)
PWK/PhJ MGP_PWKPhJ_G0018608
protein coding gene Chr11:120879651-120881831 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018399
protein coding gene Chr11:124137052-124139228 (+)
WSB/EiJ MGP_WSBEiJ_G0018894
protein coding gene Chr11:124356984-124359160 (+)



Homology
more
  • Human Ortholog
    TEX19, testis expressed 19
  • Vertebrate Orthologs
    2
  • Human Ortholog
    TEX19, testis expressed 19
    Orthology source: HGNC
  • Links
    NCBI Gene ID: 400629
    neXtProt AC: NX_Q8NA77
    UniProt: Q8NA77

  • Chr Location
    17q25.3; chr17:82359247-82363776 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    32 phenotypes from 3 alleles in 3 genetic backgrounds
    10 phenotypes from multigenic genotypes
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit decreased fertility, which in males is due to impaired spermatogenesis and increased male germ cell apoptosis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 73679 NCBI Gene Model | MGI Sequence Detail 2172 C57BL/6J ±  kb
    transcript NM_028602 RefSeq | MGI Sequence Detail 1740 C57BL/6  
    polypeptide Q99MV2 UniProt | EBI | MGI Sequence Detail 351 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 23
      cDNA 19
      Primer pair 3
      Other 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 8
      Gene Ontology 10
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:244182 MacLennan M, et al., Mobilization of LINE-1 retrotransposons is restricted by Tex19.1 in mouse embryonic stem cells. Elife. 2017 Aug 14;6

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    03/13/2019
    MGI 6.13
    The Jackson Laboratory