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Wdr75 Gene Detail
Summary
  • Symbol
    Wdr75
  • Name
    WD repeat domain 75
  • Synonyms
    1300003A18Rik, 2410118I19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920924
    NCBI Gene: 73674
Location & Maps
more
  • Sequence Map
    Chr1:45795166-45823619 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      28454 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 23.87 cM, cytoband C1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    WDR75, WD repeat domain 75
  • Vertebrate Orthologs
    10
  • Human Ortholog
    WDR75, WD repeat domain 75
    Orthology source: HGNC, HomoloGene
  • Synonyms
    NET16, UTP17
  • Links
    NCBI Gene ID: 84128
    neXtProt AC: NX_Q8IWA0

  • Chr Location
    2q32.2; chr2:189441433-189475562 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 32771
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: WDR75
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    7
  • Genomic Mutations
    1 involving Wdr75
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022347 VEGA Gene Model | MGI Sequence Detail 28454 C57BL/6J ±  kb
transcript OTTMUST00000053315 VEGA | MGI Sequence Detail 2953 Not Applicable  
polypeptide OTTMUSP00000025354 VEGA | MGI Sequence Detail 830 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    209 from dbSNP Build 142
Protein
Information
less
  • UniProt
    10 Sequences
  • InterPro Domains
    IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily
    IPR001680 WD40 repeat
    IPR017986 WD40-repeat-containing domain
    IPR015943 WD40/YVTN repeat-like-containing domain
Molecular
Reagents
less
  • All nucleic 188
    cDNA 188

    Microarray probesets 5
Other
Accession IDs
less
MGI:1921401, MGI:2138661
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:189611 Vrljicak P, et al., Twist1 transcriptional targets in the developing atrio-ventricular canal of the mouse. PLoS One. 2012;7(7):e40815

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory