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Cabp4 Gene Detail
Summary
  • Symbol
    Cabp4
  • Name
    calcium binding protein 4
  • Synonyms
    2410038D05Rik
Location &
Maps
more
  • Sequence Map
    Chr19:4185422-4189608 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 19, 3.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    33 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920910
protein coding gene Chr19:4185422-4194032 (-)
129S1/SvImJ ENSMUSG00200050136
protein coding gene Chr19:945949-951976 (-)
A/J ENSMUSG00195051751
protein coding gene Chr19:1337169-1343206 (-)
AKR/J ENSMUSG00220044158
protein coding gene Chr19:1110122-1116151 (-)
BALB/cJ ENSMUSG00180045178
protein coding gene Chr19:1711932-1717961 (-)
C3H/HeJ ENSMUSG00175009478
protein coding gene Chr19:956646-962687 (-)
C57BL/6NJ ENSMUSG00215040763
protein coding gene Chr19:1184248-1190278 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022491
protein coding gene Chr19:879489-883649 (-)
CAST/EiJ ENSTCUG00005026079
protein coding gene Chr19:1091256-1097261 (-)
CBA/J ENSMUSG00210048394
protein coding gene Chr19:956961-962997 (-)
DBA/2J ENSMUSG00185040443
protein coding gene Chr19:1333271-1339307 (-)
FVB/NJ ENSMUSG00205048906
protein coding gene Chr19:1334488-1340496 (-)
JF1/MsJ ENSUMUG00000052393
protein coding gene Chr19:1318455-1324420 (-)
LP/J ENSMUSG00230051801
protein coding gene Chr19:2252112-2258143 (-)
NOD/ShiLtJ ENSMUSG00190029371
protein coding gene Chr19:878274-884299 (-)
NZO/HlLtJ ENSMUSG00225025791
protein coding gene Chr19:5960956-5966987 (-)
PWK/PhJ ENSLUMG00010005436
protein coding gene Chr19:1095162-1101172 (-)
SPRET/EiJ ENSMSPG00010039161
protein coding gene Chr19:1075261-1079727 (-)
WSB/EiJ ENSIUOG00005045713
protein coding gene Chr19:962360-968365 (-)



Homology
more
  • Human Ortholog
    CABP4, calcium binding protein 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CABP4, calcium binding protein 4
  • Synonyms
    CRSD, CSNB2B
  • Links
    NCBI Gene ID: 57010
    UniProt: P57796

  • Chr Location
    11q13.2; chr11:67452403-67461752 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    15 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice with disruptions in this gene display structural and electrophysiological abnormalities in the retina.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic 73660 NCBI Gene Model | MGI Sequence Detail 4187 C57BL/6J ±  kb
    transcript NM_144532 RefSeq | MGI Sequence Detail 1472 Not Specified  
    polypeptide Q8VHC5 UniProt | EBI | MGI Sequence Detail 271 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 17

      Microarray probesets 2
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 3
      Gene Ontology 10
      Phenotypes 13
    • Earliest
      J:59389 Haeseleer F, et al., Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin. J Biol Chem. 2000 Jan 14;275(2):1247-60
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory