Cabp4
Gene Detail

Symbol Name ID

Cabp4 calcium binding protein 4 MGI:1920910

Synonyms

2410038D05Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 19

3.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr19:4135425-4139609 bp, - strand From Ensembl annotation of GRCm38   4185 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:16927  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Cabp4

Human homologs

Human Homolog		CABP4, calcium binding protein 4
NCBI Gene ID		57010
neXtProt AC		NX_P57796
Human Synonyms		CSNB2B
Human Chr (Location)		11q13.2; chr11:67455347-67461774 (+)  GRCh38
Disease Associations		(1) Diseases Associated with Human CABP4

Alleles and phenotypes

All alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from APF )
 

Mice with disruptions in this gene display structural and electrophysiological abnormalities in the retina.

 

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	photoreceptor cell morphogenesis, phototransduction, ...
Component	cytoplasm, cytosol
Function	calcium ion binding, metal ion binding

External Resources: FuncBase

Expression

Literature Summary: (2 records)

Data Summary: Results (56)    Tissues (9)    Images (26)
Theiler Stages: 23, 28

Assay Type	Results
RNA in situ	56

cDNA source data(15)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(16) cDNA(16)
Microarray probesets(2)

Other database links

Ensembl Gene Model	ENSMUSG00000024842 (Evidence)
Entrez Gene	73660 (Evidence)
UniGene	379226
DFCI	TC1587752, TC1597583
DoTS	DT.91334387, DT.97405226
NIA Mouse Gene Index	U019101
PDB	2M28, 2M29
Consensus CDS Project	CCDS29416.1
International Mouse Knockout Project Status	Cabp4

Sequences

Length	Strain/Species
genomic	ENSMUSG00000024842	Ensembl Gene Model | MGI Sequence Detail	4185	C57BL/6J
transcript	ENSMUST00000025761	Ensembl | MGI Sequence Detail	1431	Not Applicable
polypeptide	ENSMUSP00000025761	Ensembl | MGI Sequence Detail	271	Not Applicable

All sequences(35) RefSeq(18) UniProt(2)

Polymorphisms

SNPs within 2kb(33 from dbSNP Build 137)

Protein-related information

Resource	ID	Description
InterPro	IPR018247	EF-Hand 1, calcium-binding site
InterPro	IPR002048	EF-hand domain
InterPro	IPR011992	EF-hand-like domain
Protein Ontology	PR:000004936	calcium-binding protein 4

References

(Earliest) J:59389 Haeseleer F, et al., Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin. J Biol Chem. 2000 Jan 14;275(2):1247-60
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(32)