About   Help   FAQ
Cabp4 Gene Detail
Summary
  • Symbol
    Cabp4
  • Name
    calcium binding protein 4
  • Synonyms
    2410038D05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920910
    NCBI Gene: 73660
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr19:4135425-4139609 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4185 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 3.84 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    CABP4, calcium binding protein 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CABP4, calcium binding protein 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CRSD, CSNB2B
  • Links
    NCBI Gene ID: 57010
    neXtProt AC: NX_P57796
    UniProt: P57796

  • Chr Location
    11q13.2; chr11:67452406-67461774 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 16927
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CABP4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice with disruptions in this gene display structural and electrophysiological abnormalities in the retina.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000024842 Ensembl Gene Model | MGI Sequence Detail 4185 C57BL/6J ±  kb
    transcript ENSMUST00000025761 Ensembl | MGI Sequence Detail 1431 Not Applicable  
    polypeptide ENSMUSP00000025761 Ensembl | MGI Sequence Detail 271 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      33 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 17

      Microarray probesets 2
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 10
    • Earliest
      J:59389 Haeseleer F, et al., Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin. J Biol Chem. 2000 Jan 14;275(2):1247-60
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    07/31/2018
    MGI 6.12
    The Jackson Laboratory