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Pdxdc1 Gene Detail
Summary
  • Symbol
    Pdxdc1
  • Name
    pyridoxal-dependent decarboxylase domain containing 1
  • Synonyms
    2210010A19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920909
    NCBI Gene: 94184
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:13833148-13903131 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 9.64 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    253 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920909
protein coding gene Chr16:13833148-13903145 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022537
protein coding gene Chr16:10836103-10926350 (-)
A/J MGP_AJ_G0022499
protein coding gene Chr16:10241412-10314186 (-)
AKR/J MGP_AKRJ_G0022475
protein coding gene Chr16:10686745-10763117 (-)
BALB/cJ MGP_BALBcJ_G0022503
protein coding gene Chr16:10408043-10480630 (-)
C3H/HeJ MGP_C3HHeJ_G0022270
protein coding gene Chr16:10779622-10855562 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022952
protein coding gene Chr16:10996639-11077531 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020472
protein coding gene Chr16:10330848-10401772 (-)
CAST/EiJ MGP_CASTEiJ_G0021797
protein coding gene Chr16:10798398-10872805 (-)
CBA/J MGP_CBAJ_G0022239
protein coding gene Chr16:11533069-11613303 (-)
DBA/2J MGP_DBA2J_G0022370
protein coding gene Chr16:10230304-10303914 (-)
FVB/NJ MGP_FVBNJ_G0022346
protein coding gene Chr16:10217089-10287411 (-)
LP/J MGP_LPJ_G0022438
protein coding gene Chr16:10741010-10820352 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022368
protein coding gene Chr16:11153901-11230937 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022965
protein coding gene Chr16:10662316-10736261 (-)
PWK/PhJ MGP_PWKPhJ_G0021539
protein coding gene Chr16:10496091-10568607 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021367
protein coding gene Chr16:10651635-10725952 (-)
WSB/EiJ MGP_WSBEiJ_G0021845
protein coding gene Chr16:10680490-10759159 (-)



Homology
more
  • Human Ortholog
    PDXDC1, pyridoxal dependent decarboxylase domain containing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PDXDC1, pyridoxal dependent decarboxylase domain containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LP8165
  • Links
    NCBI Gene ID: 23042
    neXtProt AC: NX_Q6P996
    UniProt: Q6P996

  • Chr Location
    16p13.11; chr16:14974591-15139410 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 22858
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PDXDC1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022680 Ensembl Gene Model | MGI Sequence Detail 69984 C57BL/6J ±  kb
transcript ENSMUST00000023361 Ensembl | MGI Sequence Detail 4228 Not Applicable  
polypeptide ENSMUSP00000023361 Ensembl | MGI Sequence Detail 789 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • EC
  • InterPro Domains
    IPR002129 Pyridoxal phosphate-dependent decarboxylase
    IPR015424 Pyridoxal phosphate-dependent transferase
    IPR015421 Pyridoxal phosphate-dependent transferase, major domain
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 7
Other
Accession IDs
less
MGI:2146345
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory