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Spns1
Gene Detail
Symbol

Name
ID
Spns1
spinster homolog 1
MGI:1920908
Synonyms
2210013K02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 7
69.01 cM, cytoband F4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:126370060-126377450 bp, - strand
From VEGA annotation of GRCm38

  7391 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41530  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SPNS1
Gene Tree: Spns1

Human
homologs
SPNS1, spinster homolog 1 (Drosophila)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 83985
neXtProt AC: NX_Q9H2V7

Human Synonyms: HSpin1, LAT, nrs, PP2030, SPIN1, SPINL

Human Chr (Location): 16p11.2; chr16:28974771-28984762 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(7) Targeted(3)
Incidental mutations (data from APF )
 
Homozygous mutation results in lethality before weaning.
 
Interactions
Spns1 interacts with 181 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process lipid transport, locomotion, ...
Component integral component of membrane, lysosomal membrane, ...
Function sphingolipid transporter activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (10)    Tissues (7)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 10
cDNA source data(190)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase spns1    NEW 
Molecular
reagents
All nucleic(191) cDNA(191)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000031445 (Evidence)
Ensembl Gene Model ENSMUSG00000030741 (Evidence)
Entrez Gene 73658 (Evidence)
UniGene 11112
DFCI TC1602600, TC1607676, TC1573509
DoTS DT.101334322, DT.101401722, DT.533070, DT.102557674
NIA Mouse Gene Index U029240
Consensus CDS Project CCDS21826.1
International Mouse Phenotyping Consortium Status Spns1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031445 VEGA Gene Model | MGI Sequence Detail 7391 C57BL/6J ±  kb
transcript OTTMUST00000077915 VEGA | MGI Sequence Detail 2219 Not Applicable 
polypeptide OTTMUSP00000041308 VEGA | MGI Sequence Detail 528 Not Applicable 

For the selected sequences
All sequences(97) RefSeq(3) UniProt(5)
Polymorphisms
SNPs within 2kb(58 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011701 Major facilitator superfamily
InterPro IPR020846 Major facilitator superfamily domain
Protein Ontology PR:000015550 protein spinster homolog 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory