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Ccrl2
Gene Detail
 Symbol
Name
ID
Ccrl2
chemokine (C-C motif) receptor-like 2
MGI:1920904
Synonyms 1810047I05Rik, Ackr5, CCR11, Cmkbr1l2, L-CCR
Feature Type protein coding gene
Genetic Map
Chromosome 9
60.92 cM, cytoband F
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:111054835-111057270 bp, - strand
From NCBI annotation of GRCm38

  2436 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2948  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: chemokine receptor
Gene Tree: Ccrl2

Human
homologs
Human Homolog CCRL2, chemokine (C-C motif) receptor-like 2
NCBI Gene ID 9034
neXtProt AC  NX_O00421
Human Synonyms  ACKR5, CKRX, CRAM, CRAM-A, CRAM-B, HCR
Human Chr (Location)  3p21; chr3:46407230-46409523 (+)  GRCh38
Alleles
and
phenotypes
All alleles(4) : Targeted(4)
 
Mice homozygous for a targeted null mutation do not exhibit any significant abnormalities compared to controls.
 
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process chemokine-mediated signaling pathway, chemotaxis, ...
Component integral component of membrane, integral component of plasma membrane, ...
Function C-C chemokine receptor activity, CCR chemokine receptor binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (102)    Tissues (75)    Images (16)
Theiler Stages: 19, 23, 28
Assay TypeResults
RNA in situ 67
RT-PCR 35
cDNA source data(22)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(23) cDNA(22) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000043953 (Evidence)
Entrez Gene54199 (Evidence)
UniGene7336
DFCITC1583505
DoTSDT.101346274, DT.40181988, DT.99688522
NIA Mouse Gene IndexU031376
Consensus CDS ProjectCCDS23582.1
International Mouse Knockout Project StatusCcrl2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 54199 NCBI Gene Model | MGI Sequence Detail 2436 C57BL/6J ±  kb
transcript NM_017466 RefSeq | MGI Sequence Detail 2110 C57BL/6 
polypeptide O35457 UniProt | EBI | MGI Sequence Detail 360 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(6) UniProt(1)
Polymorphisms SNPs within 2kb(69 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000355 Chemokine receptor family
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001214 chemokine receptor-like protein CCRL2
Graphical View of Protein Domain Structure
References (Earliest) J:27219 Gao JL, et al., Cloning and differential tissue-specific expression of three mouse beta chemokine receptor-like genes, including the gene for a functional macrophage inflammatory protein-1 alpha receptor. J Biol Chem. 1995 Jul 21;270(29):17494-501
(Latest) J:190524 Shalom-Barak T, et al., Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory