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Vgll3 Gene Detail
Summary
  • Symbol
    Vgll3
  • Name
    vestigial like family member 3
  • Synonyms
    1700110N18Rik, Vito-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920819
    NCBI Gene: 73569
  • Gene Overview
    MyGene.info: VGLL3
  • Alliance
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:65815257-65866368 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 37.34 cM, cytoband C1.3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    508 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920819
protein coding gene Chr16:65815015-65866368 (.)
129S1/SvImJ MGP_129S1SvImJ_G0022946
protein coding gene Chr16:65362840-65410599 (+)
A/J MGP_AJ_G0022914
protein coding gene Chr16:62540067-62589380 (+)
AKR/J MGP_AKRJ_G0022884
protein coding gene Chr16:64507405-64556535 (+)
BALB/cJ MGP_BALBcJ_G0022916
protein coding gene Chr16:62763075-62810191 (+)
C3H/HeJ MGP_C3HHeJ_G0022678
protein coding gene Chr16:64804039-64852379 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023364
protein coding gene Chr16:67293353-67340587 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020867
protein coding gene Chr16:61550718-61598444 (+)
CAST/EiJ MGP_CASTEiJ_G0022201
protein coding gene Chr16:65011588-65062709 (+)
CBA/J MGP_CBAJ_G0022649
protein coding gene Chr16:70179332-70229126 (+)
DBA/2J MGP_DBA2J_G0022781
protein coding gene Chr16:62297184-62353639 (+)
FVB/NJ MGP_FVBNJ_G0022755
protein coding gene Chr16:61909957-61958464 (+)
LP/J MGP_LPJ_G0022850
protein coding gene Chr16:65151038-65203263 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022774
protein coding gene Chr16:71402053-71453733 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023380
protein coding gene Chr16:64589276-64641879 (+)
PWK/PhJ MGP_PWKPhJ_G0021944
protein coding gene Chr16:62466559-62519092 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021773
protein coding gene Chr16:64292899-64342833 (+)
WSB/EiJ MGP_WSBEiJ_G0022248
protein coding gene Chr16:64675110-64729452 (+)



Homology
more
  • Human Ortholog
    VGLL3, vestigial like family member 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    VGLL3, vestigial like family member 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    VGL3, VGL-3
  • Links
    NCBI Gene ID: 389136
    neXtProt AC: NX_A8MV65
    UniProt: A8MV65

  • Chr Location
    3p12.1; chr3:86937969-86991293 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 53442
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: VGLL3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000091243 Ensembl Gene Model | MGI Sequence Detail 51112 C57BL/6J ±  kb
transcript ENSMUST00000168064 Ensembl | MGI Sequence Detail 7009 Not Applicable  
polypeptide ENSMUSP00000131500 Ensembl | MGI Sequence Detail 325 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146708
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:190524 Shalom-Barak T, et al., Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory