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Pebp4 Gene Detail
Summary
  • Symbol
    Pebp4
  • Name
    phosphatidylethanolamine binding protein 4
  • Synonyms
    1700051A02Rik, 1700081D17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920773
    NCBI Gene: 73523
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:70077869-70297367 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 36.10 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1369 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920773
 protein coding gene Chr14:70077856-70297367 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021527
 protein coding gene Chr14:64439911-64678928 (+)
A/J MGP_AJ_G0021486
 protein coding gene Chr14:63099658-63322406 (+)
AKR/J MGP_AKRJ_G0021462
 protein coding gene Chr14:64990843-65221420 (+)
BALB/cJ MGP_BALBcJ_G0021492
 protein coding gene Chr14:62860886-63083127 (+)
C3H/HeJ MGP_C3HHeJ_G0021269
 protein coding gene Chr14:64705229-64928815 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021931
 protein coding gene Chr14:67343772-67595969 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019471
 protein coding gene Chr14:60931495-61158543 (+)
CAST/EiJ MGP_CASTEiJ_G0020786
 protein coding gene Chr14:61270200-61514274 (+)
CBA/J MGP_CBAJ_G0021236
 protein coding gene Chr14:69450722-69706025 (+)
DBA/2J MGP_DBA2J_G0021359
 protein coding gene Chr14:62479836-62703600 (+)
FVB/NJ MGP_FVBNJ_G0021338
 protein coding gene Chr14:61911360-62132443 (+)
LP/J MGP_LPJ_G0021430
 protein coding gene Chr14:65700871-65932989 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021367
 protein coding gene Chr14:68382952-68625846 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021955
 protein coding gene Chr14:64253246-64482747 (+)
PWK/PhJ MGP_PWKPhJ_G0020530
 protein coding gene Chr14:59236806-59465061 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020363
 protein coding gene Chr14:60172401-60407004 (+)
WSB/EiJ MGP_WSBEiJ_G0020839
 protein coding gene Chr14:64551027-64788248 (+)



Homology
more
  • Human Ortholog
    PEBP4, phosphatidylethanolamine binding protein 4
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PEBP4, phosphatidylethanolamine binding protein 4
  • Synonyms
    CORK1, CORK-1, GWTM1933, HEL-S-300, hPEBP4, PEBP-4, PRO4408
  • Links
    NCBI Gene ID: 157310
    neXtProt AC: NX_Q96S96
    UniProt: Q96S96

  • Chr Location
    8p21.3; chr8:22713251-23000000 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    802
  • Tissues
    15
  • cDNA Data
    15
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022085 Ensembl Gene Model | MGI Sequence Detail 219499 C57BL/6J ±  kb
transcript ENSMUST00000022678 Ensembl | MGI Sequence Detail 1079 Not Applicable  
polypeptide ENSMUSP00000022678 Ensembl | MGI Sequence Detail 242 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000012533 phosphatidylethanolamine-binding protein 4
    (term hierarchy)
  • InterPro Domains
    IPR036610 PEBP-like superfamily
    IPR001858 Phosphatidylethanolamine-binding, conserved site
    IPR008914 Phosphatidylethanolamine-binding protein
    IPR035810 Phosphatidylethanolamine-binding protein, eukaryotic
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 4
Other
Accession IDs
less
MGI:1920634, MGI:2145638
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:330836 Luo Q, et al., Phosphatidylethanolamine-binding protein 4 deficiency exacerbates carbon tetrachloride-induced liver fibrosis by regulating the NF-kappaB signaling pathway. Front Pharmacol. 2022;13:964829
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory