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Mbd3l1 Gene Detail
Summary
  • Symbol
    Mbd3l1
  • Name
    methyl-CpG binding domain protein 3-like 1
  • Synonyms
    1700070G05Rik, 1700095H13Rik, Mbd3l
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920753
    NCBI Gene: 73503
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:18389655-18396594 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 7.06 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920753
 protein coding gene Chr9:18389655-18396594 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034377
 protein coding gene Chr9:15508571-15516523 (+)
A/J MGP_AJ_G0034356
 protein coding gene Chr9:15381483-15388384 (+)
AKR/J MGP_AKRJ_G0034284
 protein coding gene Chr9:15521079-15528292 (+)
BALB/cJ MGP_BALBcJ_G0034348
 protein coding gene Chr9:15204355-15211652 (+)
C3H/HeJ MGP_C3HHeJ_G0034061
 protein coding gene Chr9:15808671-15816668 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034871
 protein coding gene Chr9:16096882-16104036 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031808
 protein coding gene Chr9:14461748-14467870 (+)
CAST/EiJ MGP_CASTEiJ_G0033387
 protein coding gene Chr9:15652081-15660054 (+)
CBA/J MGP_CBAJ_G0034034
 protein coding gene Chr9:16773129-16786609 (+)
DBA/2J MGP_DBA2J_G0034191
 protein coding gene Chr9:15230670-15237499 (+)
FVB/NJ MGP_FVBNJ_G0034135
 protein coding gene Chr9:14789263-14796944 (+)
LP/J MGP_LPJ_G0034277
 protein coding gene Chr9:15733575-15746891 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034180
 protein coding gene Chr9:17918824-17926222 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034890
 protein coding gene Chr9:15514656-15522892 (+)
PWK/PhJ MGP_PWKPhJ_G0033093
 protein coding gene Chr9:15287173-15294675 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032928
 protein coding gene Chr9:15552806-15559566 (+)
WSB/EiJ MGP_WSBEiJ_G0033504
 protein coding gene Chr9:15308350-15319679 (+)



Homology
more
  • Human Ortholog
    MBD3L1, methyl-CpG binding domain protein 3 like 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MBD3L1, methyl-CpG binding domain protein 3 like 1
  • Synonyms
    MBD3L
  • Links
    NCBI Gene ID: 85509
    neXtProt AC: NX_Q8WWY6
    UniProt: Q8WWY6

  • Chr Location
    19p13.2; chr19:8832377-8843340 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    2 phenotype references
Homozygous null mice are viable and fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 73503 NCBI Gene Model | MGI Sequence Detail 6940 C57BL/6J ±  kb
transcript NM_028557 RefSeq | MGI Sequence Detail 888 C57BL/6  
polypeptide Q9D9H3 UniProt | EBI | MGI Sequence Detail 186 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000010217 methyl-CpG-binding domain protein 3-like 1
    (term hierarchy)
  • InterPro Domains
    IPR032343 Methyl-CpG-binding domain protein 2/3, p55-binding region
    IPR025884 Methyl-CpG binding protein 2/3, C-terminal domain
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
Other
Accession IDs
less
MGI:1925722
References
more
  • Summaries
    All 24
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:156017 Yokoyama S, et al., A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory