Ms4a13 Gene Detail

Summary

• Symbol
  Ms4a13
• Name
  membrane-spanning 4-domains, subfamily A, member 13
• Synonyms
  1700060E18Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1920716
  NCBI Gene: 73466
• Member of
  Ms4ac cluster
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr19:11169418-11196737 bp, - strand
• From NCBI annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 19, 7.92 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  190 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1920716	protein coding gene	Chr19:11169418-11196737 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0024871	protein coding gene	Chr19:8563858-8590360 (-)
A/J	MGP_AJ_G0024839	protein coding gene	Chr19:7997706-8030863 (-)
AKR/J	MGP_AKRJ_G0024814	protein coding gene	Chr19:8299807-8328942 (-)
BALB/cJ	MGP_BALBcJ_G0024839	protein coding gene	Chr19:8034603-8062205 (-)
C3H/HeJ	MGP_C3HHeJ_G0024605	protein coding gene	Chr19:8184486-8214038 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0025287	protein coding gene	Chr19:8953465-8981846 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022714	protein coding gene	Chr19:8409486-8435927 (-)
CAST/EiJ	MGP_CASTEiJ_G0024078	protein coding gene	Chr19:7828410-7856670 (-)
CBA/J	MGP_CBAJ_G0024579	protein coding gene	Chr19:8995492-9025918 (-)
DBA/2J	MGP_DBA2J_G0024706	protein coding gene	Chr19:7991716-8019293 (-)
FVB/NJ	MGP_FVBNJ_G0024673	protein coding gene	Chr19:8028825-8052149 (-)
LP/J	MGP_LPJ_G0024793	protein coding gene	Chr19:8518151-8546572 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0024700	protein coding gene	Chr19:8881761-8915126 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025335	protein coding gene	Chr19:8328256-8354904 (-)
PWK/PhJ	MGP_PWKPhJ_G0023823	protein coding gene	Chr19:7449923-7475030 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0023628	protein coding gene	Chr19:7528264-7555409 (-)
WSB/EiJ	MGP_WSBEiJ_G0024140	protein coding gene	Chr19:8214652-8247342 (-)

Homology

• Human Ortholog
  MS4A13, membrane spanning 4-domains A13

• Vertebrate Orthologs
  7

• Human Ortholog
  MS4A13, membrane spanning 4-domains A13
  Orthology source: HomoloGene, HGNC
• Links
  HGNC:16674

  NCBI Gene ID: 503497

  neXtProt AC: NX_Q5J8X5

  UniProt: Q5J8X5

  
  
• Chr Location
  chr11:60515382-60543424 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 77851
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 macaque, rhesus
  
• HCOP
  human homology predictions: MS4A13
• Gene Tree
  Ms4a13
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  8 strains or lines available

Male mice homozygous for a mutation are viable and show normal fertility.

Gene Ontology
(GO)
Classifications

• All GO Annotations
  3
• GO References
  2

• External Resources
  FuncBase

Expression

• cDNA Data
  3

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Interactions

• Ms4a13 interacts with 98 markers (Mir1a-1, Mir1a-2, Mir15a, ...) View All

Sequences &
Gene Models

• All Sequences
  33
• RefSeq
  4
• UniProt
  1
• CCDS
  CCDS29595.1, CCDS84420.1
• UniGene
  272723

• Ensembl
  ENSMUSG00000057240 (Evidence)
• NCBI Gene
  73466

Representative Sequences			Length	Strain/Species
genomic	73466	NCBI Gene Model | MGI Sequence Detail	27320	C57BL/6J
transcript	NM_198224	RefSeq | MGI Sequence Detail	1375	C57BL/6
polypeptide	Q5FWC3	UniProt | EBI | MGI Sequence Detail	203	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000010653 membrane-spanning 4-domains subfamily A member 13
  (term hierarchy)
• InterPro Domains
  IPR007237 CD20-like family
  IPR030417 Membrane-spanning 4-domains subfamily A

Molecular
Reagents

• All nucleic 3

  cDNA 3

  
  

  Microarray probesets 3

References

• Summaries
  All 20

  Gene Ontology 2

  Phenotypes 1
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:234235 Miyata H, et al., Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7704-10

TSS for Ms4a13:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr158300	Chr19:11196700-11196742 (-)	16 bp
Tssr158299	Chr19:11196684-11196692 (-)	49 bp