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Aldh3b3 Gene Detail
Summary
  • Symbol
    Aldh3b3
  • Name
    aldehyde dehydrogenase 3 family, member B3
  • Synonyms
    1700055N04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920708
    NCBI Gene: 73458
  • Gene Overview
    MyGene.info: ALDH3B2
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:3958645-3972103 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 3.68 cM, cytoband A
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    26 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920708
protein coding gene Chr19:3958645-3972419 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024635
protein coding gene Chr19:771850-790131 (+)
A/J MGP_AJ_G0024602
protein coding gene Chr19:735096-749788 (+)
AKR/J MGP_AKRJ_G0024573
protein coding gene Chr19:767336-773847 (+)
BALB/cJ MGP_BALBcJ_G0024600
protein coding gene Chr19:746282-760359 (+)
C3H/HeJ MGP_C3HHeJ_G0024369
protein coding gene Chr19:745056-766765 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025048
protein coding gene Chr19:781038-797551 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022477
protein coding gene Chr19:708796-713278 (+)
CAST/EiJ MGP_CASTEiJ_G0023841
protein coding gene Chr19:773404-779256 (+)
CBA/J MGP_CBAJ_G0024339
protein coding gene Chr19:847627-874459 (+)
DBA/2J MGP_DBA2J_G0024468
protein coding gene Chr19:713285-728959 (+)
FVB/NJ MGP_FVBNJ_G0024435
protein coding gene Chr19:732985-737667 (+)
LP/J MGP_LPJ_G0024554
protein coding gene Chr19:766574-781331 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024465
protein coding gene Chr19:811423-826499 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025096
protein coding gene Chr19:752006-768617 (+)
PWK/PhJ MGP_PWKPhJ_G0023587
protein coding gene Chr19:745424-764397 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023394
protein coding gene Chr19:767221-773498 (+)
WSB/EiJ MGP_WSBEiJ_G0023904
protein coding gene Chr19:745387-765157 (+)



Homology
more
  • Human Ortholog
    ALDH3B2, aldehyde dehydrogenase 3 family member B2
  • Vertebrate Orthologs
    2
  • Human Ortholog
    ALDH3B2, aldehyde dehydrogenase 3 family member B2
    Orthology source: HGNC
  • Synonyms
    ALDH8
  • Links
    NCBI Gene ID: 222
    UniProt: P48448

  • Chr Location
    11q13.2; chr11:67662162-67681214 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037263 Ensembl Gene Model | MGI Sequence Detail 13459 C57BL/6J ±  kb
transcript ENSMUST00000179433 Ensembl | MGI Sequence Detail 3827 Not Applicable  
polypeptide ENSMUSP00000136334 Ensembl | MGI Sequence Detail 479 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • EC
  • InterPro Domains
    IPR016163 Aldehyde dehydrogenase, C-terminal
    IPR016160 Aldehyde dehydrogenase, cysteine active site
    IPR015590 Aldehyde dehydrogenase domain
    IPR029510 Aldehyde dehydrogenase, glutamic acid active site
    IPR012394 Aldehyde dehydrogenase NAD(P)-dependent
    IPR016162 Aldehyde dehydrogenase, N-terminal
    IPR016161 Aldehyde/histidinol dehydrogenase
Molecular
Reagents
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  • All nucleic 5
    cDNA 5

    Microarray probesets 7
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Gene Ontology 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:218413 Kitamura T, et al., Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification. Biochem J. 2015 Jan 1;465(1):79-87

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory