Smim33 Gene Detail

Summary

• Symbol
  Smim33
• Name
  small integral membrane protein 33
• Synonyms
  1700066B19Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1920699
  NCBI Gene: 73449
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr18:35859895-35863922 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 18, 19.22 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  22 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1920699	protein coding gene	Chr18:35836278-35863922 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0024268	protein coding gene	Chr18:34033237-34061737 (+)
A/J	MGP_AJ_G0024234	protein coding gene	Chr18:32857544-32884913 (+)
AKR/J	MGP_AKRJ_G0024202	protein coding gene	Chr18:33790897-33818092 (+)
BALB/cJ	MGP_BALBcJ_G0024234	protein coding gene	Chr18:32902456-32929794 (+)
C3H/HeJ	MGP_C3HHeJ_G0024001	protein coding gene	Chr18:33812693-33846784 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0024675	protein coding gene	Chr18:35252608-35282256 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022115	protein coding gene	Chr18:32961537-32989992 (+)
CAST/EiJ	MGP_CASTEiJ_G0023476	protein coding gene	Chr18:33795550-33826457 (+)
CBA/J	MGP_CBAJ_G0023969	protein coding gene	Chr18:36269741-36307450 (+)
DBA/2J	MGP_DBA2J_G0024101	protein coding gene	Chr18:32490977-32518969 (+)
FVB/NJ	MGP_FVBNJ_G0024068	protein coding gene	Chr18:32181504-32208677 (+)
LP/J	MGP_LPJ_G0024183	protein coding gene	Chr18:34085457-34115130 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0024096	protein coding gene	Chr18:37497462-37528786 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0024724	protein coding gene	Chr18:33622962-33650643 (+)
PWK/PhJ	MGP_PWKPhJ_G0023220	protein coding gene	Chr18:32715010-32744602 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0023027	protein coding gene	Chr18:33887590-33921464 (+)
WSB/EiJ	MGP_WSBEiJ_G0023539	protein coding gene	Chr18:33550995-33582524 (+)

Homology

• Human Ortholog
  SMIM33, small integral membrane protein 33

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  SMIM33, small integral membrane protein 33
  
• Links
  HGNC:53645

  NCBI Gene ID: 111064649

  UniProt: A0A1B0GW64

  
  
• Chr Location
  5q31.2

---

• Alliance of Genome Resources
  Smim33 stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: SMIM33
• Gene Tree
  Smim33
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Find Mice (IMSR)
  2 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  1

Expression

• Assay Results
  672
• cDNA Data
  5

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Interactions

• Smim33 interacts with 230 markers (Mir1a-1, Mir1a-2, Mir18, ...) View All

Sequences &
Gene Models

• All Sequences
  30
• RefSeq
  4
• UniProt
  1
• CCDS
  CCDS50252.1

• Ensembl
  ENSMUSG00000073598 (Evidence)
• NCBI Gene
  73449

Representative Sequences			Length	Strain/Species
genomic	73449	NCBI Gene Model | MGI Sequence Detail	4028	C57BL/6J
transcript	NM_001033168	RefSeq | MGI Sequence Detail	2504	C57BL/6
polypeptide	Q3TS39	UniProt | EBI | MGI Sequence Detail	127	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000059669 small integral membrane protein 33
  (term hierarchy)
• InterPro Domains
  IPR038803 Small integral membrane protein 33

Molecular
Reagents

• All nucleic 5

  cDNA 5

  
  

  Microarray probesets 2

References

• Summaries
  All 20

  Gene Ontology 1

  Phenotypes 2
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Smim33:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr150547	Chr18:35859915-35859941 (+)	33 bp
Tssr150548	Chr18:35860028-35860047 (+)	143 bp
Tssr150549	Chr18:35860072-35860092 (+)	187 bp