Timm21 Gene Detail

Summary

• Symbol
  Timm21
• Name
  tranlocase of inner mitochondrial membrane 21
• Synonyms
  1700034H14Rik, 2700002I20Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1920595
  NCBI Gene: 67105

Location & Maps

• Sequence Map
  Chr18:84947294-84951524 bp, - strand
• From Ensembl annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    4231 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 18, 57.53 cM, cytoband E3
• Mapping Data
  2 experiments

Homology

• Human Ortholog
  TIMM21, translocase of inner mitochondrial membrane 21

• Vertebrate Orthologs
  10

• Human Ortholog
  TIMM21, translocase of inner mitochondrial membrane 21
  Orthology source: HomoloGene, HGNC
• Synonyms
  C18orf55, HSPC154, TIM21
• Links
  HGNC:25010

  NCBI Gene ID: 29090

  neXtProt AC: NX_Q9BVV7

  UniProt: Q9BVV7

  
  
• Chr Location
  18q22.3; chr18:74148511-74158969 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 32211
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: TIMM21
• Gene Tree
  Timm21
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  6
• Gene trapped
  1
• Targeted
  4
• Transposon induced
  1
• Genomic Mutations
  1 involving Timm21
• Incidental Mutations
  APF
• Find Mice (IMSR)
  16 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  14
• GO References
  4

• External Resources
  FuncBase

Expression

• cDNA Data
  78

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase timm21

Interactions

• Timm21 interacts with 75 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

Sequences &
Gene Models

• All Sequences
  24
• RefSeq
  6
• UniProt
  3
• CCDS
  CCDS29386.1
• UniGene
  250617

• Ensembl
  ENSMUSG00000024645 (Evidence)
• NCBI Gene
  67105

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000024645	Ensembl Gene Model | MGI Sequence Detail	4231	C57BL/6J
transcript	ENSMUST00000025547	Ensembl | MGI Sequence Detail	1315	Not Applicable
polypeptide	ENSMUSP00000025547	Ensembl | MGI Sequence Detail	244	Not Applicable

Polymorphisms

• SNPs within 2kb
  70 from dbSNP Build 142

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000030615 mitochondrial import inner membrane translocase subunit Tim21
  (term hierarchy)
• InterPro Domains
  IPR013261 Mitochondrial import inner membrane translocase subunit Tim21

Molecular
Reagents

• All nucleic 78

  cDNA 78

  
  

  Microarray probesets 3

Other
Accession IDs

MGI:1914355

References

• Summaries
  All 29

  Gene Ontology 4

  Phenotypes 5
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42