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Nptxr
Gene Detail
 Symbol
Name
ID
Nptxr
neuronal pentraxin receptor
MGI:1920590
Synonyms 1200009K17Rik, 1700036C17Rik, 5730406O18Rik, D15Bwg0580e, NPCD, NPR
Feature Type protein coding gene
Genetic Map
Chromosome 15
37.85 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr15:79786353-79804766 bp, - strand
From VEGA annotation of GRCm38

  18414 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8620  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 2 zebrafish

Gene Tree: Nptxr

Human
homologs
Human Homolog NPTXR, neuronal pentraxin receptor
NCBI Gene ID 23467
neXtProt AC  NX_O95502
Human Synonyms  NPR
Human Chr (Location)  22q13.1; chr22:38818451-38844012 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Radiation induced(1) Targeted(3)
Genomic Mutations involving Nptxr (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation of this gene display a mild alteration in retinal ganglion cell innervation but are fertile with no obvious behavioral abnormalities.
 
Interactions
Nptxr interacts with 270 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process signal transduction
Component extracellular space, plasma membrane
Function pentraxin receptor activity, protein complex binding
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (25)    Tissues (16)    Images (2)
Theiler Stages: 19, 23
Assay TypeResults
RNA in situ 25
cDNA source data(13)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(15) Genomic(1) cDNA(13) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000034820 (Evidence)
Ensembl Gene ModelENSMUSG00000022421 (Evidence)
Entrez Gene73340 (Evidence)
Consensus CDS ProjectCCDS27653.1
International Mouse Knockout Project StatusNptxr
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034820 VEGA Gene Model | MGI Sequence Detail 18414 C57BL/6J ±  kb
transcript OTTMUST00000042348 VEGA | MGI Sequence Detail 5004 Not Applicable 
polypeptide OTTMUSP00000019030 VEGA | MGI Sequence Detail 493 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(2)
Polymorphisms SNPs within 2kb(153 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000011384 neuronal pentraxin receptor
References (Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)
Other
accession IDs
MGD-MRK-34009, MGI:106317, MGI:1921368, MGI:1921988, MGI:2146019, MGI:2146057

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory