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Ube2d2b Gene Detail
Summary
  • Symbol
    Ube2d2b
  • Name
    ubiquitin-conjugating enzyme E2D 2B
  • Synonyms
    1700013N18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920568
    NCBI Gene: 73318
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:107978028-107979643 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 52.23 cM, cytoband E5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    18 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920568
 protein coding gene Chr5:107977965-107979643 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029846
 protein coding gene Chr5:109884323-109886000 (+)
A/J MGP_AJ_G0029810
 protein coding gene Chr5:105667952-105669629 (+)
AKR/J MGP_AKRJ_G0029755
 protein coding gene Chr5:109076840-109078517 (+)
BALB/cJ MGP_BALBcJ_G0029822
 protein coding gene Chr5:106798401-106800078 (+)
C3H/HeJ MGP_C3HHeJ_G0029544
 protein coding gene Chr5:109525721-109527398 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030276
 protein coding gene Chr5:114374106-114375783 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027510
 protein coding gene Chr5:100726557-100728226 (+)
CAST/EiJ MGP_CASTEiJ_G0028958
 protein coding gene Chr5:108463276-108464953 (+)
CBA/J MGP_CBAJ_G0029512
 protein coding gene Chr5:118228530-118230207 (+)
DBA/2J MGP_DBA2J_G0029658
 protein coding gene Chr5:105806394-105808071 (+)
FVB/NJ MGP_FVBNJ_G0029615
 protein coding gene Chr5:104529635-104531312 (+)
LP/J MGP_LPJ_G0029746
 protein coding gene Chr5:110467978-110469655 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029647
 protein coding gene Chr5:123122839-123124516 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030310
 protein coding gene Chr5:108643318-108644995 (+)
PWK/PhJ MGP_PWKPhJ_G0028671
 protein coding gene Chr5:104610559-104612236 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028509
 protein coding gene Chr5:106159391-106161067 (+)
WSB/EiJ MGP_WSBEiJ_G0029031
 protein coding gene Chr5:108936948-108938625 (+)



Homology
more
  • Human Ortholog
    UBE2D4, ubiquitin conjugating enzyme E2 D4 (putative)
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UBE2D4, ubiquitin conjugating enzyme E2 D4 (putative)
  • Synonyms
    HBUCE1
  • Links
    NCBI Gene ID: 51619
    neXtProt AC: NX_Q9Y2X8
    UniProt: Q9Y2X8

  • Chr Location
    7p13; chr7:43926436-43956136 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    3 involving Ube2d2b
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    10 strains or lines available
Male mice homozygous for a null allele exhibit normal fecundity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    11
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 73318 NCBI Gene Model | MGI Sequence Detail 1616 C57BL/6J ±  kb
transcript NM_001276397 RefSeq | MGI Sequence Detail 1616 C57BL/6  
polypeptide Q6ZWY6 UniProt | EBI | MGI Sequence Detail 147 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 2
References
more
  • Summaries
    All 29
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:279039 Lu Y, et al., CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice. Biol Reprod. 2019 Aug 1;101(2):501-511
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory