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Calr3
Gene Detail
Symbol

Name
ID
Calr3
calreticulin 3
MGI:1920566
Synonyms
1700031L01Rik, 6330586I20Rik, calsperin, Crt2
Feature Type
protein coding gene
Genetic Map
Chromosome 8
35.08 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:72424176-72443870 bp, - strand
From VEGA annotation of GRCm38

  19695 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:57091  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog

Protein SuperFamily: calreticulin
Gene Tree: Calr3

Human
homologs
Human Homolog CALR3, calreticulin 3
NCBI Gene ID 125972
neXtProt AC  NX_Q96L12
Human Synonyms  CMH19, CRT2, CT93
Human Chr (Location)  19p13.11; chr19:16479057-16496192 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human CALR3
Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(10) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit male infertility associated with impaired zona pellucida binding and fertilization.
 
Interactions
Calr3 interacts with 89 markers (Mir17, Mir20a, Mir20b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell differentiation, protein folding, ...
Component endoplasmic reticulum
Function calcium ion binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (4)    Tissues (4)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 4
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(9) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000031770 (Evidence)
Ensembl Gene ModelENSMUSG00000019732 (Evidence)
Entrez Gene73316 (Evidence)
UniGene196315
DFCITC1585828, TC1593332
DoTSDT.526837, DT.91328537
NIA Mouse Gene IndexU029963
Consensus CDS ProjectCCDS22413.1, CCDS40388.1
International Mouse Knockout Project StatusCalr3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031770 VEGA Gene Model | MGI Sequence Detail 19695 C57BL/6J ±  kb
transcript OTTMUST00000078711 VEGA | MGI Sequence Detail 1769 Not Applicable 
polypeptide OTTMUSP00000041895 VEGA | MGI Sequence Detail 380 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(195 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009169 Calreticulin
InterPro IPR001580 Calreticulin/calnexin
InterPro IPR018124 Calreticulin/calnexin, conserved site
InterPro IPR009033 Calreticulin/calnexin, P domain
InterPro IPR008985 Concanavalin A-like lectin/glucanases superfamily
InterPro IPR013320 Concanavalin A-like lectin/glucanase, subgroup
Protein Ontology PR:000004985 calreticulin-3
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:182133 Tokuhiro K, et al., Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male fertility. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3850-5
All references(33)
Other
accession IDs
MGI:1924129

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory