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Rhobtb3
Gene Detail
Symbol

Name
ID
Rhobtb3
Rho-related BTB domain containing 3
MGI:1920546
Synonyms
1700040C17Rik, 2610033K01Rik, 4930503C18Rik, mKIAA0878
Feature Type
protein coding gene
Genetic Map
Chromosome 13
40.95 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr13:75869537-75943925 bp, - strand
From VEGA annotation of GRCm38

  74389 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8932  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Rhobtb3

Human
homologs
Human Homolog RHOBTB3, Rho-related BTB domain containing 3
NCBI Gene ID 22836
neXtProt AC  NX_O94955
Human Chr (Location)  5q15; chr5:95731146-95796367 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rhobtb3 interacts with 332 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (29 annotations)
Process ATP catabolic process, retrograde transport, endosome to Golgi, ...
Component cell, cytoplasm, ...
Function 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity, ATPase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (361)    Tissues (58)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 332
Northern blot 21
RT-PCR 8
cDNA source data(56)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(58) cDNA(57) Primer pair(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000023271 (Evidence)
Ensembl Gene ModelENSMUSG00000021589 (Evidence)
Entrez Gene73296 (Evidence)
UniGene276200
DFCITC1587883, TC1597984, TC1600397, TC1666735
DoTSDT.101380822, DT.101738094, DT.526235, DT.55171074, DT.91384040, DT.91403243
NIA Mouse Gene IndexU034979
EC3.6.1.-
Consensus CDS ProjectCCDS26652.1
International Mouse Knockout Project StatusRhobtb3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023271 VEGA Gene Model | MGI Sequence Detail 74389 C57BL/6J ±  kb
transcript OTTMUST00000056338 VEGA | MGI Sequence Detail 4980 Not Applicable 
polypeptide OTTMUSP00000027066 VEGA | MGI Sequence Detail 611 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(8) UniProt(2)
Polymorphisms
SNPs within 2kb(931 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013069 BTB/POZ
InterPro IPR011333 BTB/POZ fold
InterPro IPR000210 BTB/POZ-like
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
Protein Ontology PR:000032331 rho-related BTB domain-containing protein 3
References
(Earliest) J:735 Noonan DM, et al., The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule. J Biol Chem. 1991 Dec 5;266(34):22939-47
(Latest) J:213427 Adissu HA, et al., Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen. Dis Model Mech. 2014 May;7(5):515-24
All references(47)
Other
accession IDs
MGI:1916481, MGI:1922044, MGI:2145203, MGI:2145421

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory