About   Help   FAQ
Vps50 Gene Detail
Summary
  • Symbol
    Vps50
  • Name
    VPS50 EARP/GARPII complex subunit
  • Synonyms
    1700034M03Rik, 8430415E05Rik, Ccdc132, mKIAA1861
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920538
    NCBI Gene: 73288
  • Gene Overview
    MyGene.info: VPS50
Location & Maps
more
  • Sequence Map
    Chr6:3498382-3603531 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      105150 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 1.81 cM, cytoband A1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    VPS50, VPS50, EARP/GARPII complex subunit
  • Vertebrate Orthologs
    10
  • Human Ortholog
    VPS50, VPS50, EARP/GARPII complex subunit
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CCDC132, VPS54L
  • Links
    NCBI Gene ID: 55610
    neXtProt AC: NX_Q96JG6

  • Chr Location
    7q21.3; chr7:93232340-93361123 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 11498
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: VPS50
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035289 VEGA Gene Model | MGI Sequence Detail 105150 C57BL/6J ±  kb
transcript OTTMUST00000090017 VEGA | MGI Sequence Detail 3788 Not Applicable  
polypeptide OTTMUSP00000049280 VEGA | MGI Sequence Detail 964 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    182 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000032453 syndetin
  • InterPro Domains
    IPR019514 Protein of unknown function DUF2451, C-terminal
    IPR019515 Vacuolar protein sorting-associated protein 54, N-terminal
Molecular
Reagents
less
  • All nucleic 93
    cDNA 93

    Microarray probesets 4
Other
Accession IDs
less
MGI:1918738, MGI:2141784
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:225569 Schindler C, et al., EARP is a multisubunit tethering complex involved in endocytic recycling. Nat Cell Biol. 2015 May;17(5):639-50

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/27/2016
MGI 6.05
The Jackson Laboratory