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Ddit4l Gene Detail
Summary
  • Symbol
    Ddit4l
  • Name
    DNA-damage-inducible transcript 4-like
  • Synonyms
    1700037B15Rik, 1700108M02Rik, REDD2, RTP801L
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920534
    NCBI Gene: 73284
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:137623672-137628332 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 63.81 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    49 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920534
 protein coding gene Chr3:137621612-137628333 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027916
 protein coding gene Chr3:140634731-140641442 (+)
A/J MGP_AJ_G0027873
 protein coding gene Chr3:135676260-135682979 (+)
AKR/J MGP_AKRJ_G0027839
 protein coding gene Chr3:139284366-139291081 (+)
BALB/cJ MGP_BALBcJ_G0027886
 protein coding gene Chr3:135491407-135498192 (+)
C3H/HeJ MGP_C3HHeJ_G0027615
 protein coding gene Chr3:139603128-139609855 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028329
 protein coding gene Chr3:145507126-145511925 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025667
 protein coding gene Chr3:130789045-130793814 (+)
CAST/EiJ MGP_CASTEiJ_G0027071
 protein coding gene Chr3:139353416-139361255 (+)
CBA/J MGP_CBAJ_G0027592
 protein coding gene Chr3:150458341-150465062 (+)
DBA/2J MGP_DBA2J_G0027731
 protein coding gene Chr3:134801674-134808399 (+)
FVB/NJ MGP_FVBNJ_G0027698
 protein coding gene Chr3:132250410-132257209 (+)
LP/J MGP_LPJ_G0027841
 protein coding gene Chr3:142048086-142054811 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027730
 protein coding gene Chr3:158565097-158571896 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028387
 protein coding gene Chr3:138823714-138830940 (+)
PWK/PhJ MGP_PWKPhJ_G0026795
 protein coding gene Chr3:134544779-134551606 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026622
 protein coding gene Chr3:136916188-136920892 (+)
WSB/EiJ MGP_WSBEiJ_G0027151
 protein coding gene Chr3:139618511-139625565 (+)



Homology
more
  • Human Ortholog
    DDIT4L, DNA damage inducible transcript 4 like
  • Vertebrate Orthologs
    8
  • Human Ortholog
    DDIT4L, DNA damage inducible transcript 4 like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    REDD2, Rtp801L
  • Links
    NCBI Gene ID: 115265
    neXtProt AC: NX_Q96D03
    UniProt: Q96D03

  • Chr Location
    4q24; chr4:100185870-100190498 (-)  GRCh38.p7
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    64
  • Tissues
    15
  • cDNA Data
    28
  • Literature Summary
    7
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 73284 NCBI Gene Model | MGI Sequence Detail 4661 C57BL/6J ±  kb
transcript NM_030143 RefSeq | MGI Sequence Detail 2721 C57BL/6  
polypeptide Q8VHZ5 UniProt | EBI | MGI Sequence Detail 193 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    cDNA 28
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1925887
References
more
  • Summaries
    All 37
    Developmental Gene Expression 7
    Diseases 1
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:244068 Bohnenpoll T, et al., A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development. PLoS Genet. 2017 Aug;13(8):e1006951
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/08/2019
MGI 6.14 		The Jackson Laboratory