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Snorc Gene Detail
Summary
  • Symbol
    Snorc
  • Name
    secondary ossification center associated regulator of chondrocyte maturation
  • Synonyms
    3110079O15Rik, Snorc
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920484
    NCBI Gene: 73234
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:87470271-87475482 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 44.41 cM, cytoband C5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    32 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920484
protein coding gene Chr1:87470130-87475482 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016265
protein coding gene Chr1:88828200-88833412 (+)
A/J MGP_AJ_G0016246
protein coding gene Chr1:85502034-85507246 (+)
AKR/J MGP_AKRJ_G0016207
protein coding gene Chr1:88022511-88027722 (+)
BALB/cJ MGP_BALBcJ_G0016203
protein coding gene Chr1:85619284-85624495 (+)
C3H/HeJ MGP_C3HHeJ_G0016031
protein coding gene Chr1:88281621-88286833 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016659
protein coding gene Chr1:92143268-92148422 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014381
protein coding gene Chr1:79952746-79957941 (+)
CAST/EiJ MGP_CASTEiJ_G0015616
protein coding gene Chr1:87501268-87506504 (+)
CBA/J MGP_CBAJ_G0016007
protein coding gene Chr1:95064688-95069898 (+)
DBA/2J MGP_DBA2J_G0016110
protein coding gene Chr1:84801511-84806714 (+)
FVB/NJ MGP_FVBNJ_G0016109
protein coding gene Chr1:83863452-83868660 (+)
LP/J MGP_LPJ_G0016181
protein coding gene Chr1:89891615-89896862 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016135
protein coding gene Chr1:98344574-98349785 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016702
protein coding gene Chr1:88133801-88139004 (+)
PWK/PhJ MGP_PWKPhJ_G0015403
protein coding gene Chr1:84102755-84108057 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015183
protein coding gene Chr1:87053221-87058431 (+)
WSB/EiJ MGP_WSBEiJ_G0015680
protein coding gene Chr1:87807066-87812275 (+)



Homology
more
  • Human Ortholog
    SNORC, secondary ossification center associated regulator of chondrocyte maturation
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SNORC, secondary ossification center associated regulator of chondrocyte maturation
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ASCL830, C2orf82, UNQ830
  • Links
    NCBI Gene ID: 389084
    neXtProt AC: NX_Q6UX34
    UniProt: Q6UX34

  • Chr Location
    2q37.1; chr2:232865678-232878700 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Reduced viability of homozygous mutants is seen. Surviving male homozygous mutant mice exhibit decreased mean serum triglyceride levels when compared with controls. Female homozygous mutants exhibit decreased activity levels during the 12-hour habituation period of home-cage activity testing.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000026258 Ensembl Gene Model | MGI Sequence Detail 5212 C57BL/6J ±  kb
    transcript ENSMUST00000027476 Ensembl | MGI Sequence Detail 478 Not Applicable  
    polypeptide ENSMUSP00000027476 Ensembl | MGI Sequence Detail 121 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • InterPro Domains
      IPR031500 Protein SNORC
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 2
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 10
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:250431 Heinonen J, et al., Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency. Osteoarthritis Cartilage. 2017 Jul;25(7):1132-1142

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory