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Siral2 Gene Detail
Summary
  • Symbol
    Siral2
  • Name
    SIR2 antiphage like 2
  • Synonyms
    3110048E14Rik, C230014M12Rik, Fam118a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920475
    NCBI Gene: 73225
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:84913149-84947031 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 40.25 cM, cytoband E3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    853 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920475
 protein coding gene Chr15:84913149-85001781 (+)
129S1/SvImJ ENSMUSG00200035496
 protein coding gene Chr15:82041682-82068311 (+)
A/J ENSMUSG00195018342
 protein coding gene Chr15:81968007-81994640 (+)
AKR/J ENSMUSG00220025912
 protein coding gene Chr15:82022357-82049888 (+)
BALB/cJ ENSMUSG00180014938
 protein coding gene Chr15:81844806-81871445 (+)
C3H/HeJ ENSMUSG00175026912
 protein coding gene Chr15:82155672-82182301 (+)
C57BL/6NJ ENSMUSG00215026011
 protein coding gene Chr15:81940058-81966690 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020122
 protein coding gene Chr15:79036229-79062723 (+)
CAST/EiJ ENSTCUG00005026590
 protein coding gene Chr15:81439076-81465057 (+)
CBA/J ENSMUSG00210013083
 protein coding gene Chr15:81930572-81957201 (+)
DBA/2J ENSMUSG00185021279
 protein coding gene Chr15:81968627-81995203 (+)
FVB/NJ ENSMUSG00205027521
 protein coding gene Chr15:81717868-81744321 (+)
JF1/MsJ ENSUMUG00000019663
 protein coding gene Chr15:81493007-81519592 (+)
LP/J ENSMUSG00230044401
 protein coding gene Chr15:85281896-85308524 (+)
NOD/ShiLtJ ENSMUSG00190021379
 protein coding gene Chr15:81955262-81982793 (+)
NZO/HlLtJ ENSMUSG00225046966
 protein coding gene Chr15:85623300-85649933 (+)
PWK/PhJ ENSLUMG00010028456
 protein coding gene Chr15:81700472-81726860 (+)
SPRET/EiJ ENSMSPG00010012238
 protein coding gene Chr15:83351471-83377847 (+)
WSB/EiJ ENSIUOG00005010242
 protein coding gene Chr15:82033416-82059704 (+)



Homology
more
  • Human Ortholog
    SIRAL2, SIR2 antiphage like 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SIRAL2, SIR2 antiphage like 2
  • Synonyms
    C22orf8, FAM118A
  • Links
    NCBI Gene ID: 55007
    UniProt: Q9NWS6

  • Chr Location
    22q13.31; chr22:45308960-45342824 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    31 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    617
  • Tissues
    2
  • cDNA Data
    47
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022434 Ensembl Gene Model | MGI Sequence Detail 33883 C57BL/6J ±  kb
transcript ENSMUST00000023069 Ensembl | MGI Sequence Detail 2518 Not Applicable  
polypeptide ENSMUSP00000023069 Ensembl | MGI Sequence Detail 357 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 47
    cDNA 47

    Microarray probesets 3
Other
Accession IDs
less
MGI:2443288, MGI:8327518
References
more
  • Summaries
    All 56
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 3
    Phenotypes 31
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory