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Xpot Gene Detail
Summary
  • Symbol
    Xpot
  • Name
    exportin, tRNA (nuclear export receptor for tRNAs)
  • Synonyms
    1110004L07Rik, C79645, EXPORTIN-T
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920442
    NCBI Gene: 73192
  • Gene Overview
    MyGene.info: XPOT
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:121587380-121626332 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 69.86 cM, cytoband D3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    437 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920442
protein coding gene Chr10:121587380-121626523 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017784
protein coding gene Chr10:124872439-124914333 (-)
A/J MGP_AJ_G0017759
protein coding gene Chr10:119878339-119923550 (-)
AKR/J MGP_AKRJ_G0017722
protein coding gene Chr10:123459859-123503150 (-)
BALB/cJ MGP_BALBcJ_G0017723
protein coding gene Chr10:120278360-120345615 (-)
C3H/HeJ MGP_C3HHeJ_G0017547
protein coding gene Chr10:123673022-123713517 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018178
protein coding gene Chr10:129116783-129159555 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015858
protein coding gene Chr10:114208595-114248883 (-)
CAST/EiJ MGP_CASTEiJ_G0017107
protein coding gene Chr10:124056026-124101819 (-)
CBA/J MGP_CBAJ_G0017516
protein coding gene Chr10:134376946-134430805 (-)
DBA/2J MGP_DBA2J_G0017622
protein coding gene Chr10:119008499-119051222 (-)
FVB/NJ MGP_FVBNJ_G0017617
protein coding gene Chr10:117999163-118049169 (-)
LP/J MGP_LPJ_G0017696
protein coding gene Chr10:125398589-125444851 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0018218
protein coding gene Chr10:123510518-123559147 (-)
PWK/PhJ MGP_PWKPhJ_G0016892
protein coding gene Chr10:119133874-119177055 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016683
protein coding gene Chr10:122382828-122423753 (-)
WSB/EiJ MGP_WSBEiJ_G0017168
protein coding gene Chr10:123713895-123754568 (-)



Homology
more
  • Human Ortholog
    XPOT, exportin for tRNA
  • Vertebrate Orthologs
    9
  • Human Ortholog
    XPOT, exportin for tRNA
    Orthology source: HomoloGene, HGNC
  • Synonyms
    XPO3
  • Links
    NCBI Gene ID: 11260
    neXtProt AC: NX_O43592
    UniProt: O43592

  • Chr Location
    12q14.2; chr12:64404350-64451125 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 38291
    1 human;1 mouse;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: XPOT
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    • All Sequences
    • RefSeq
    • UniProt
    • UniGene
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034667 Ensembl Gene Model | MGI Sequence Detail 38953 C57BL/6J ±  kb
    transcript ENSMUST00000039810 Ensembl | MGI Sequence Detail 5992 Not Applicable  
    polypeptide ENSMUSP00000043488 Ensembl | MGI Sequence Detail 963 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 118
      cDNA 118

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1923534, MGI:2143613, MGI:2143928
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 12
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory