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Pcdh18 Gene Detail
Summary
  • Symbol
    Pcdh18
  • Name
    protocadherin 18
  • Synonyms
    PCDH68L
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920423
    NCBI Gene: 73173
  • Gene Overview
    MyGene.info: PCDH18
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:49743296-49757325 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 21.67 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    137 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920423
protein coding gene Chr3:49743291-49757382 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027191
protein coding gene Chr3:48188071-48202088 (-)
A/J MGP_AJ_G0027151
protein coding gene Chr3:46781444-46795535 (-)
AKR/J MGP_AKRJ_G0027120
protein coding gene Chr3:47742083-47756054 (-)
BALB/cJ MGP_BALBcJ_G0027163
protein coding gene Chr3:46685734-46699701 (-)
C3H/HeJ MGP_C3HHeJ_G0026906
protein coding gene Chr3:47944676-47958643 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027609
protein coding gene Chr3:50151594-50165608 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024969
protein coding gene Chr3:43522864-43536911 (-)
CAST/EiJ MGP_CASTEiJ_G0026359
protein coding gene Chr3:47978206-47992211 (-)
CBA/J MGP_CBAJ_G0026883
protein coding gene Chr3:51718782-51732749 (-)
DBA/2J MGP_DBA2J_G0027017
protein coding gene Chr3:46435114-46449085 (-)
FVB/NJ MGP_FVBNJ_G0026985
protein coding gene Chr3:45442892-45456859 (-)
LP/J MGP_LPJ_G0027129
protein coding gene Chr3:48970392-48984417 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027003
protein coding gene Chr3:55902708-55916679 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027668
protein coding gene Chr3:47640834-47654843 (-)
PWK/PhJ MGP_PWKPhJ_G0026091
protein coding gene Chr3:46034731-46048732 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025904
protein coding gene Chr3:47297907-47311975 (-)
WSB/EiJ MGP_WSBEiJ_G0026433
protein coding gene Chr3:47759559-47773542 (-)



Homology
more
  • Human Ortholog
    PCDH18, protocadherin 18
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PCDH18, protocadherin 18
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PCDH68L
  • Links
    NCBI Gene ID: 54510
    neXtProt AC: NX_Q9HCL0
    UniProt: Q9HCL0

  • Chr Location
    4q28.3; chr4:137518918-137532530 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000037892 Ensembl Gene Model | MGI Sequence Detail 14030 C57BL/6J ±  kb
    transcript ENSMUST00000035931 Ensembl | MGI Sequence Detail 5168 Not Applicable  
    polypeptide ENSMUSP00000039245 Ensembl | MGI Sequence Detail 1134 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 86
      cDNA 86

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2140021
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 7
      Diseases 1
      Gene Ontology 5
      Phenotypes 11
    • Earliest
      J:64276 Lyon MF, et al., Dose-response curves for radiation-induced gene mutations in mouse oocytes and their interpretation. Mutat Res. 1979 Nov;63(1):161-73
    • Latest
      J:245960 Piprek RP, et al., Cell adhesion molecules expression pattern indicates that somatic cells arbitrate gonadal sex of differentiating bipotential fetal mouse gonad. Mech Dev. 2017 Oct;147:17-27

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory