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Rwdd3 Gene Detail
Summary
  • Symbol
    Rwdd3
  • Name
    RWD domain containing 3
  • Synonyms
    2510027J23Rik, 3110037C01Rik, RSUME
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920420
    NCBI Gene: 66568
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:120949047-120965344 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 52.94 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    198 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920420
 protein coding gene Chr3:120949046-120965427 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027827
 protein coding gene Chr3:123327054-123343130 (-)
A/J MGP_AJ_G0027785
 protein coding gene Chr3:119217298-119233395 (-)
AKR/J MGP_AKRJ_G0027751
 protein coding gene Chr3:122246938-122263153 (-)
BALB/cJ MGP_BALBcJ_G0027797
 protein coding gene Chr3:119042912-119058995 (-)
C3H/HeJ MGP_C3HHeJ_G0027528
 protein coding gene Chr3:122647102-122663578 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028243
 protein coding gene Chr3:127809449-127827145 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025582
 protein coding gene Chr3:114662922-114680016 (-)
CAST/EiJ MGP_CASTEiJ_G0026984
 protein coding gene Chr3:122010006-122026136 (-)
CBA/J MGP_CBAJ_G0027503
 protein coding gene Chr3:132118030-132134111 (-)
DBA/2J MGP_DBA2J_G0027644
 protein coding gene Chr3:118375238-118391565 (-)
FVB/NJ MGP_FVBNJ_G0027612
 protein coding gene Chr3:115982525-115998476 (-)
LP/J MGP_LPJ_G0027754
 protein coding gene Chr3:124841055-124857131 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027642
 protein coding gene Chr3:139770004-139786086 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028299
 protein coding gene Chr3:121802688-121818778 (-)
PWK/PhJ MGP_PWKPhJ_G0026710
 protein coding gene Chr3:118055593-118072420 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026533
 protein coding gene Chr3:119849680-119866775 (-)
WSB/EiJ MGP_WSBEiJ_G0027064
 protein coding gene Chr3:122506701-122522859 (-)



Homology
more
  • Human Ortholog
    RWDD3, RWD domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RWDD3, RWD domain containing 3
  • Synonyms
    RSUME
  • Links
    NCBI Gene ID: 25950
    neXtProt AC: NX_Q9Y3V2
    UniProt: Q9Y3V2

  • Chr Location
    1p21.3; chr1:95234155-95247225 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    17
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028133 Ensembl Gene Model | MGI Sequence Detail 16298 C57BL/6J ±  kb
transcript ENSMUST00000106467 Ensembl | MGI Sequence Detail 1158 Not Applicable  
polypeptide ENSMUSP00000102075 Ensembl | MGI Sequence Detail 339 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    Genomic 2
    cDNA 18

    Microarray probesets 5
Other
Accession IDs
less
MGI:1913818, MGI:2139616, MGI:2139778
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory