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Prss57
Gene Detail
Symbol

Name
ID
Prss57
protease, serine 57
MGI:1920356
Synonyms
2900092M14Rik, GLGL782, Prssl1, UNQ782
Feature Type
protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:79781476-79790961 bp, - strand
From VEGA annotation of GRCm38

  9486 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:133812  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 2 western clawed frog; 25 zebrafish

HCOP human homology predictions: PRSS57
Protein SuperFamily: trypsin
Gene Tree: Prss57

Human
homologs
PRSS57, protease, serine, 57
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 400668
neXtProt AC: NX_Q6UWY2

Human Synonyms: NSP4, PRSSL1, UNQ782

Human Chr (Location): 19p13.3; chr19:685546-695531 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Prss57 interacts with 194 markers (Mir1a-1, Mir1a-2, Mir10a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process proteolysis
Component extracellular region
Function hydrolase activity, peptidase activity, ...
External Resources: FuncBase
Expression
cDNA source data(7)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100497492    NEW 
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(1)
Other database
links
VEGA Gene Model OTTMUSG00000035141 (Evidence)
Ensembl Gene Model ENSMUSG00000020323 (Evidence)
Entrez Gene 73106 (Evidence)
UniGene 491308
DFCI TC1606746
NIA Mouse Gene Index U031992
EC 3.4.21.-
Consensus CDS Project CCDS35968.1
International Mouse Phenotyping Consortium Status Prss57
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035141 VEGA Gene Model | MGI Sequence Detail 9486 C57BL/6J ±  kb
transcript OTTMUST00000089485 VEGA | MGI Sequence Detail 2841 Not Applicable 
polypeptide OTTMUSP00000048908 VEGA | MGI Sequence Detail 284 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(13) UniProt(3)
Polymorphisms
SNPs within 2kb(11 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000013331 serine protease 57
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory