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Prss57 Gene Detail
Summary
  • Symbol
    Prss57
  • Name
    protease, serine 57
  • Synonyms
    2900092M14Rik, GLGL782, Prssl1, UNQ782
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920356
    NCBI Gene: 73106
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:79781474-79790961 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920356
protein coding gene Chr10:79781474-79794740 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017460
protein coding gene Chr10:80325168-80334651 (-)
A/J MGP_AJ_G0017438
protein coding gene Chr10:77534853-77544203 (-)
AKR/J MGP_AKRJ_G0017399
protein coding gene Chr10:79642322-79651592 (-)
BALB/cJ MGP_BALBcJ_G0017400
protein coding gene Chr10:77761010-77770455 (-)
C3H/HeJ MGP_C3HHeJ_G0017223
protein coding gene Chr10:79751312-79761071 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017854
protein coding gene Chr10:83100386-83109865 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015542
protein coding gene Chr10:73760442-73770498 (-)
CAST/EiJ MGP_CASTEiJ_G0016790
protein coding gene Chr10:79924204-79940955 (-)
CBA/J MGP_CBAJ_G0017195
protein coding gene Chr10:86325295-86334771 (-)
DBA/2J MGP_DBA2J_G0017301
protein coding gene Chr10:76749914-76759402 (-)
FVB/NJ MGP_FVBNJ_G0017295
protein coding gene Chr10:75921246-75932136 (-)
LP/J MGP_LPJ_G0017372
protein coding gene Chr10:80808908-80819733 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017321
protein coding gene Chr10:88306952-88315970 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017895
protein coding gene Chr10:79621705-79631168 (-)
PWK/PhJ MGP_PWKPhJ_G0016571
protein coding gene Chr10:76609019-76619386 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016360
protein coding gene Chr10:78599890-78611426 (-)
WSB/EiJ MGP_WSBEiJ_G0016850
protein coding gene Chr10:79651634-79661142 (-)



Homology
more
  • Human Ortholog
    PRSS57, serine protease 57
  • Vertebrate Orthologs
    34
  • Human Ortholog
    PRSS57, serine protease 57
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NSP4, PRSSL1, UNQ782
  • Links
    NCBI Gene ID: 400668
    neXtProt AC: NX_Q6UWY2
    UniProt: Q6UWY2

  • Chr Location
    19p13.3; chr19:685521-695461 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020323 Ensembl Gene Model | MGI Sequence Detail 9488 C57BL/6J ±  kb
transcript ENSMUST00000169684 Ensembl | MGI Sequence Detail 2841 Not Applicable  
polypeptide ENSMUSP00000132215 Ensembl | MGI Sequence Detail 284 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 1
References
more
  • Summaries
    All 32
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory