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Slc25a42 Gene Detail
Summary
  • Symbol
    Slc25a42
  • Name
    solute carrier family 25, member 42
  • Synonyms
    2900084M01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920345
    NCBI Gene: 73095
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:70636990-70664931 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 34.15 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    582 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920345
 protein coding gene Chr8:70636990-70664955 (-)
129S1/SvImJ ENSMUSG00200029582
 protein coding gene Chr8:65436104-65463938 (-)
A/J ENSMUSG00195013054
 protein coding gene Chr8:65766532-65794511 (-)
AKR/J ENSMUSG00220021207
 protein coding gene Chr8:65681762-65709014 (-)
BALB/cJ ENSMUSG00180024809
 protein coding gene Chr8:65412476-65440309 (-)
C3H/HeJ ENSMUSG00175021272
 protein coding gene Chr8:65692443-65720276 (-)
C57BL/6NJ ENSMUSG00215030797
 protein coding gene Chr8:65369362-65397334 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031135
 protein coding gene Chr8:62391676-62419484 (-)
CAST/EiJ ENSTCUG00005032582
 protein coding gene Chr8:65167124-65195205 (-)
CBA/J ENSMUSG00210031020
 protein coding gene Chr8:65458000-65485828 (-)
DBA/2J ENSMUSG00185010315
 protein coding gene Chr8:71617615-71645446 (-)
FVB/NJ ENSMUSG00205024581
 protein coding gene Chr8:64962214-64990051 (-)
JF1/MsJ ENSUMUG00000023346
 protein coding gene Chr8:73895296-73923310 (-)
LP/J ENSMUSG00230031619
 protein coding gene Chr8:75229171-75257002 (-)
NOD/ShiLtJ ENSMUSG00190020950
 protein coding gene Chr8:65376007-65403983 (-)
NZO/HlLtJ ENSMUSG00225047262
 protein coding gene Chr8:78638690-78666466 (-)
PWK/PhJ ENSLUMG00010031996
 protein coding gene Chr8:65353762-65381706 (-)
SPRET/EiJ ENSMSPG00010034772
 protein coding gene Chr8:67043153-67071223 (-)
WSB/EiJ ENSIUOG00005024240
 protein coding gene Chr8:66249262-66276471 (-)



Homology
more
  • Human Ortholog
    SLC25A42, solute carrier family 25 member 42
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC25A42, solute carrier family 25 member 42
  • Synonyms
    MECREN
  • Links
    NCBI Gene ID: 284439
    UniProt: Q86VD7

  • Chr Location
    19p13.11; chr19:19061697-19113030 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    47
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    30
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 73095 NCBI Gene Model | MGI Sequence Detail 27942 C57BL/6J ±  kb
    transcript NM_001007570 RefSeq | MGI Sequence Detail 3181 C57BL/6  
    polypeptide Q8R0Y8 UniProt | EBI | MGI Sequence Detail 318 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000031993 solute carrier family 25 member 42
      (term hierarchy)
    • InterPro Domains
      IPR014762 DNA mismatch repair, conserved site
      IPR002067 Mitochondrial carrier protein
      IPR023395 Mitochondrial carrier protein domain superfamily
      IPR018108 Mitochondrial carrier protein, transmembrane region
      IPR002167 Solute carrier family 25 member 16-like
    • GlyGen
      Q8R0Y8 2 sites, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 31
      cDNA 30
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 42
      Gene Ontology 11
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory