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Ppil6 Gene Detail
Summary
  • Symbol
    Ppil6
  • Name
    peptidylprolyl isomerase (cyclophilin)-like 6
  • Synonyms
    2900084F20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920325
    NCBI Gene: 73075
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:41366435-41390282 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 22.43 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    542 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920325
 protein coding gene Chr10:41366414-41390286 (+)
129S1/SvImJ ENSMUSG00200008366
 protein coding gene Chr10:38237496-38261332 (+)
A/J ENSMUSG00195015928
 protein coding gene Chr10:38527919-38551772 (+)
AKR/J ENSMUSG00220025494
 protein coding gene Chr10:38204422-38228276 (+)
BALB/cJ ENSMUSG00180015699
 protein coding gene Chr10:38613041-38636890 (+)
C3H/HeJ ENSMUSG00175011758
 protein coding gene Chr10:38407312-38431160 (+)
C57BL/6NJ ENSMUSG00215006313
 protein coding gene Chr10:38156637-38180485 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015269
 protein coding gene Chr10:36952706-36977094 (+)
CAST/EiJ ENSTCUG00005026288
 protein coding gene Chr10:38603398-38627242 (+)
CBA/J ENSMUSG00210025088
 protein coding gene Chr10:38300778-38324630 (+)
DBA/2J ENSMUSG00185006744
 protein coding gene Chr10:38453430-38477285 (+)
FVB/NJ ENSMUSG00205010677
 protein coding gene Chr10:38368587-38392430 (+)
JF1/MsJ ENSUMUG00000032622
 protein coding gene Chr10:38227132-38253944 (+)
LP/J ENSMUSG00230005825
 protein coding gene Chr10:40227358-40251193 (+)
NOD/ShiLtJ ENSMUSG00190024456
 protein coding gene Chr10:38581610-38605465 (+)
NZO/HlLtJ ENSMUSG00225016035
 protein coding gene Chr10:44546428-44570275 (+)
PWK/PhJ ENSLUMG00010007446
 protein coding gene Chr10:38358575-38382437 (+)
SPRET/EiJ ENSMSPG00010019405
 protein coding gene Chr10:39390305-39413796 (+)
WSB/EiJ ENSIUOG00005014942
 protein coding gene Chr10:38139195-38163059 (+)



Homology
more
  • Human Ortholog
    PPIL6, peptidylprolyl isomerase like 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPIL6, peptidylprolyl isomerase like 6
  • Synonyms
    bA425D10.6, dJ919F19.1, PPIase, RSPH12
  • Links
    NCBI Gene ID: 285755
    UniProt: Q8IXY8

  • Chr Location
    6q21; chr6:109390215-109441171 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Ppil6
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    15 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000078451 Ensembl Gene Model | MGI Sequence Detail 23848 C57BL/6J ±  kb
transcript ENSMUST00000105507 Ensembl | MGI Sequence Detail 1068 Not Applicable  
polypeptide ENSMUSP00000101146 Ensembl | MGI Sequence Detail 313 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000013088 probable inactive peptidyl-prolyl cis-trans isomerase-like 6
    (term hierarchy)
  • EC
    5.2.1.8
  • InterPro Domains
    IPR029000 Cyclophilin-like domain superfamily
    IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase
    IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 2
References
more
  • Summaries
    All 32
    Gene Ontology 1
    Phenotypes 14
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory