Glrx5
Gene Detail

Symbol Name ID

Glrx5 glutaredoxin 5 homolog (S. cerevisiae) MGI:1920296

Synonyms

2310004O13Rik, 2900070E19Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 12

55.04 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr12:105032689-105040910 bp, + strand From NCBI annotation of GRCm38   8222 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:31984  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: monothiol glutaredoxin
Gene Tree: Glrx5

Human homologs

Human Homolog		GLRX5, glutaredoxin 5
NCBI Gene ID		51218
neXtProt AC		NX_Q86SX6
Human Synonyms		C14orf87, FLB4739, GRX5, PR01238, PRO1238
Human Chr (Location)		14q32.13; chr14:96001323-96011055 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human GLRX5

Alleles and phenotypes

All alleles(5) : Targeted(1) Gene trapped(4)

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	cell redox homeostasis, oxidation-reduction process
Component	mitochondrion, nucleus
Function	2 iron, 2 sulfur cluster binding, electron carrier activity, ...

External Resources: FuncBase

Expression

cDNA source data(81)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(83) cDNA(83)
Microarray probesets(2)

Other database links

Ensembl Gene Model	ENSMUSG00000021102 (Evidence)
Entrez Gene	73046 (Evidence)
UniGene	29128
DFCI	TC1577647
DoTS	DT.110940295, DT.495278
NIA Mouse Gene Index	U014335
Consensus CDS Project	CCDS26154.1
International Mouse Knockout Project Status	Glrx5

Sequences

Length	Strain/Species
genomic	73046	NCBI Gene Model | MGI Sequence Detail	8222	C57BL/6J
transcript	NM_028419	RefSeq | MGI Sequence Detail	930	C57BL/6
polypeptide	Q80Y14	UniProt | EBI | MGI Sequence Detail	152	Not Applicable

All sequences(19) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(12 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002109	Glutaredoxin
InterPro	IPR004480	Monothiol glutaredoxin-related
InterPro	IPR012336	Thioredoxin-like fold
Protein Ontology	PR:000008050	glutaredoxin-related protein 5

Graphical View of Protein Domain Structure

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23
All references(31)

Other accession IDs

MGI:1916773, MGI:2144971