About   Help   FAQ
Glrx5
Gene Detail
Symbol

Name
ID
Glrx5
glutaredoxin 5 homolog (S. cerevisiae)
MGI:1920296
Synonyms
2310004O13Rik, 2900070E19Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 12
55.04 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:105032689-105040910 bp, + strand
From NCBI annotation of GRCm38

  8222 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31984  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: GLRX5
Protein SuperFamily: monothiol glutaredoxin
Gene Tree: Glrx5

Human
homologs
GLRX5, glutaredoxin 5
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 51218
neXtProt AC: NX_Q86SX6

Human Synonyms: C14orf87, FLB4739, GRX5, PR01238, PRO1238, PRSA

Human Chr (Location): 14q32.13; chr14:95534986-95544718 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human GLRX5

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(4) Targeted(2)
Interactions
Glrx5 interacts with 63 markers (Mir22, Mir26a-2, Mir26b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell redox homeostasis
Component dendrite, mitochondrion, ...
Function 2 iron, 2 sulfur cluster binding, electron carrier activity, ...
External Resources: FuncBase
Expression
cDNA source data(43)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase glrx5    NEW 
Molecular
reagents
All nucleic(45) cDNA(45)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000021102 (Evidence)
Entrez Gene 73046 (Evidence)
UniGene 490286
DFCI TC1577647
DoTS DT.110940295, DT.495278
NIA Mouse Gene Index U014335
Consensus CDS Project CCDS26154.1
International Mouse Phenotyping Consortium Status Glrx5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 73046 NCBI Gene Model | MGI Sequence Detail 8222 C57BL/6J ±  kb
transcript NM_028419 RefSeq | MGI Sequence Detail 930 C57BL/6 
polypeptide Q80Y14 UniProt | EBI | MGI Sequence Detail 152 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(28 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002109 Glutaredoxin
InterPro IPR004480 Monothiol glutaredoxin-related
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000008050 glutaredoxin-related protein 5
Graphical View of Protein Domain Structure
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23
All references(33)
Other
accession IDs
MGI:1916773, MGI:2144971

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/30/2015
MGI 5.22
The Jackson Laboratory