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Glrx5
Gene Detail
 Symbol
Name
ID
Glrx5
glutaredoxin 5 homolog (S. cerevisiae)
MGI:1920296
Synonyms 2310004O13Rik, 2900070E19Rik
Feature Type protein coding gene
Genetic Map
Chromosome 12
55.04 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:105032689-105040910 bp, + strand
From NCBI annotation of GRCm38

  8222 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31984  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 zebrafish

Protein SuperFamily: monothiol glutaredoxin
Gene Tree: Glrx5

Human
homologs
Human Homolog GLRX5, glutaredoxin 5
NCBI Gene ID 51218
neXtProt AC  NX_Q86SX6
Human Synonyms  C14orf87, FLB4739, GRX5, PR01238, PRO1238
Human Chr (Location)  14q32.13; chr14:95534986-95544718 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human GLRX5
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(4) Targeted(2)
Interactions
Glrx5 interacts with 63 markers (Mir22, Mir26a-2, Mir26b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell redox homeostasis
Component mitochondrion, nucleus
Function 2 iron, 2 sulfur cluster binding, electron carrier activity, ...
External Resources: FuncBase
Expression
cDNA source data(43)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(45) cDNA(45)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000021102 (Evidence)
Entrez Gene73046 (Evidence)
UniGene490286
DFCITC1577647
DoTSDT.110940295, DT.495278
NIA Mouse Gene IndexU014335
Consensus CDS ProjectCCDS26154.1
International Mouse Knockout Project StatusGlrx5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 73046 NCBI Gene Model | MGI Sequence Detail 8222 C57BL/6J ±  kb
transcript NM_028419 RefSeq | MGI Sequence Detail 930 C57BL/6 
polypeptide Q80Y14 UniProt | EBI | MGI Sequence Detail 152 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(28 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002109 Glutaredoxin
InterPro IPR004480 Monothiol glutaredoxin-related
InterPro IPR012336 Thioredoxin-like fold
Protein Ontology PR:000008050 glutaredoxin-related protein 5
Graphical View of Protein Domain Structure
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23
All references(33)
Other
accession IDs
MGI:1916773, MGI:2144971

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory