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Glrx5 Gene Detail
Summary
  • Symbol
    Glrx5
  • Name
    glutaredoxin 5
  • Synonyms
    2310004O13Rik, 2900070E19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920296
    NCBI Gene: 73046
  • Gene Overview
    MyGene.info: GLRX5
Location & Maps
more
  • Sequence Map
    Chr12:105032689-105040910 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8222 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 55.04 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    GLRX5, glutaredoxin 5
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GLRX5, glutaredoxin 5
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C14orf87, FLB4739, GRX5, PR01238, PRO1238, PRSA, SIDBA3, SPAHGC
  • Links
    NCBI Gene ID: 51218
    neXtProt AC: NX_Q86SX6

  • Chr Location
    14q32.13; chr14:95534986-95544718 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    3 with human GLRX5 associations

Human Disease Mouse Models
       Anemia, Sideroblastic, 2, Pyridoxine-Refractory; SIDBA2   OMIM: 205950
Anemia, Sideroblastic, 3, Pyridoxine-Refractory; SIDBA3   OMIM: 616860
Spasticity, Childhood-Onset, with Hyperglycinemia; SPAHGC   OMIM: 616859
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Targeted
    2
  • Genomic Mutations
    1 involving Glrx5
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 73046 NCBI Gene Model | MGI Sequence Detail 8222 C57BL/6J ±  kb
transcript NM_028419 RefSeq | MGI Sequence Detail 1002 C57BL/6  
polypeptide Q80Y14 UniProt | EBI | MGI Sequence Detail 152 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    28 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 45
    cDNA 45

    Microarray probesets 2
Other
Accession IDs
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MGI:1916773, MGI:2144971
References
more
  • Summaries
    All 30
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:151002 Pagliarini DJ, et al., A mitochondrial protein compendium elucidates complex I disease biology. Cell. 2008 Jul 11;134(1):112-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory