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Rnf169 Gene Detail
Summary
  • Symbol
    Rnf169
  • Name
    ring finger protein 169
  • Synonyms
    2900057K09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920257
    NCBI Gene: 108937
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:99920254-99980448 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 54.22 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    457 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920257
protein coding gene Chr7:99920254-99980694 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032560
protein coding gene Chr7:102756424-102831698 (-)
A/J MGP_AJ_G0032534
protein coding gene Chr7:100197677-100262360 (-)
AKR/J MGP_AKRJ_G0032470
protein coding gene Chr7:102581322-102645484 (-)
BALB/cJ MGP_BALBcJ_G0032545
protein coding gene Chr7:99865474-99932307 (-)
C3H/HeJ MGP_C3HHeJ_G0032260
protein coding gene Chr7:102939300-103009486 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033043
protein coding gene Chr7:106678445-106744630 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030037
protein coding gene Chr7:102599717-102659304 (-)
CAST/EiJ MGP_CASTEiJ_G0031587
protein coding gene Chr7:94469467-94539786 (-)
CBA/J MGP_CBAJ_G0032227
protein coding gene Chr7:110364861-110432115 (-)
DBA/2J MGP_DBA2J_G0032378
protein coding gene Chr7:98521813-98587980 (-)
FVB/NJ MGP_FVBNJ_G0032335
protein coding gene Chr7:98318006-98382483 (-)
LP/J MGP_LPJ_G0032468
protein coding gene Chr7:104123417-104193191 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032368
protein coding gene Chr7:111774354-111847212 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033065
protein coding gene Chr7:101843981-101913284 (-)
PWK/PhJ MGP_PWKPhJ_G0031305
protein coding gene Chr7:91621003-91689749 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031148
protein coding gene Chr7:89148880-89218507 (-)
WSB/EiJ MGP_WSBEiJ_G0031704
protein coding gene Chr7:102526684-102603932 (-)



Homology
more
  • Human Ortholog
    RNF169, ring finger protein 169
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RNF169, ring finger protein 169
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 254225
    neXtProt AC: NX_Q8NCN4
    UniProt: Q8NCN4

  • Chr Location
    11q13.4; chr11:74748856-74842413 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 47510
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: RNF169
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000058761 Ensembl Gene Model | MGI Sequence Detail 60195 C57BL/6J ±  kb
    transcript ENSMUST00000080817 Ensembl | MGI Sequence Detail 7147 Not Applicable  
    polypeptide ENSMUSP00000079631 Ensembl | MGI Sequence Detail 694 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 52
      cDNA 52

      Microarray probesets 4
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 16
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    01/08/2019
    MGI 6.13
    The Jackson Laboratory