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Ciz1 Gene Detail
Summary
  • Symbol
    Ciz1
  • Name
    CDKN1A interacting zinc finger protein 1
  • Synonyms
    0610038H21Rik, 2900056O04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920234
    NCBI Gene: 68379
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:32252724-32268311 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 22.09 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    411 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920234
 protein coding gene Chr2:32242339-32270982 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025603
 protein coding gene Chr2:30797810-30830982 (+)
A/J MGP_AJ_G0025580
 protein coding gene Chr2:29496849-29525254 (+)
AKR/J MGP_AKRJ_G0025550
 protein coding gene Chr2:30551245-30581253 (+)
BALB/cJ MGP_BALBcJ_G0025577
 protein coding gene Chr2:29622222-29651046 (+)
C3H/HeJ MGP_C3HHeJ_G0025337
 protein coding gene Chr2:30440953-30472640 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026021
 protein coding gene Chr2:31743987-31773040 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023430
 protein coding gene Chr2:28233641-28251209 (+)
CAST/EiJ MGP_CASTEiJ_G0024799
 protein coding gene Chr2:30380153-30408591 (+)
CBA/J MGP_CBAJ_G0025315
 protein coding gene Chr2:32938489-32969510 (+)
DBA/2J MGP_DBA2J_G0025448
 protein coding gene Chr2:29263965-29294184 (+)
FVB/NJ MGP_FVBNJ_G0025410
 protein coding gene Chr2:29139845-29170556 (+)
LP/J MGP_LPJ_G0025534
 protein coding gene Chr2:30677490-30708836 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025441
 protein coding gene Chr2:32601037-32630335 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026079
 protein coding gene Chr2:30430974-30462572 (+)
PWK/PhJ MGP_PWKPhJ_G0024547
 protein coding gene Chr2:29168337-29197418 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024347
 protein coding gene Chr2:30589812-30619373 (+)
WSB/EiJ MGP_WSBEiJ_G0024868
 protein coding gene Chr2:30603228-30635399 (+)



Homology
more
  • Human Ortholog
    CIZ1, CDKN1A interacting zinc finger protein 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CIZ1, CDKN1A interacting zinc finger protein 1
  • Synonyms
    LSFR1, NP94, ZNF356
  • Links
    NCBI Gene ID: 25792
    UniProt: Q9ULV3

  • Chr Location
    9q34.11; chr9:128161251-128204482 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit decreased body size and sex specific effects on motor phenotypes.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1053
  • Tissues
    104
  • cDNA Data
    11
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68379 NCBI Gene Model | MGI Sequence Detail 15588 C57BL/6J ±  kb
    transcript NM_001252534 RefSeq | MGI Sequence Detail 3116 C57BL/6  
    polypeptide NP_082688 RefSeq | MGI Sequence Detail 845 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      18 Sequences
    • InterPro Domains
      IPR026811 Cip1-interacting zinc finger protein
      IPR000690 Matrin/U1-C, C2H2-type zinc finger
      IPR003604 Matrin/U1-C-like, C2H2-type zinc finger
      IPR036236 Zinc finger C2H2 superfamily
      IPR013087 Zinc finger C2H2-type
      IPR022755 Zinc finger, double-stranded RNA binding
    • GlyGen
      Q8VEH2 2 sites
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 13
      Primer pair 6
      Antibodies 3

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1915629
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 4
      Phenotypes 14
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:324592 Sofi S, et al., Prion-like domains drive CIZ1 assembly formation at the inactive X chromosome. J Cell Biol. 2022 Apr 4;221(4):e202103185
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    06/09/2026
    MGI 6.24     		The Jackson Laboratory