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Thap12 Gene Detail
Summary
  • Symbol
    Thap12
  • Name
    THAP domain containing 12
  • Synonyms
    2900052B10Rik, Dap4, Prkrir
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920231
    NCBI Gene: 72981
  • Gene Overview
    MyGene.info: THAP12
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:98703128-98718062 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 53.86 cM, cytoband F1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    92 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920231
protein coding gene Chr7:98703103-98718062 (.)
129S1/SvImJ MGP_129S1SvImJ_G0032542
protein coding gene Chr7:101449041-101463979 (+)
A/J MGP_AJ_G0032516
protein coding gene Chr7:98942377-98957316 (+)
AKR/J MGP_AKRJ_G0032452
protein coding gene Chr7:101293259-101308197 (+)
BALB/cJ MGP_BALBcJ_G0032527
protein coding gene Chr7:98629057-98643995 (+)
C3H/HeJ MGP_C3HHeJ_G0032242
protein coding gene Chr7:101646127-101661075 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033025
protein coding gene Chr7:105370240-105385198 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030020
protein coding gene Chr7:101373139-101388371 (+)
CAST/EiJ MGP_CASTEiJ_G0031569
protein coding gene Chr7:93173760-93188698 (+)
CBA/J MGP_CBAJ_G0032209
protein coding gene Chr7:108958590-108973538 (+)
DBA/2J MGP_DBA2J_G0032361
protein coding gene Chr7:97274392-97289343 (+)
FVB/NJ MGP_FVBNJ_G0032318
protein coding gene Chr7:97073300-97088238 (+)
LP/J MGP_LPJ_G0032450
protein coding gene Chr7:102779947-102794884 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032350
protein coding gene Chr7:110472634-110488006 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033047
protein coding gene Chr7:100556918-100571849 (+)
PWK/PhJ MGP_PWKPhJ_G0031287
protein coding gene Chr7:90358330-90373273 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031130
protein coding gene Chr7:87846988-87866381 (+)
WSB/EiJ MGP_WSBEiJ_G0031686
protein coding gene Chr7:101225381-101240312 (+)



Homology
more
  • Human Ortholog
    THAP12, THAP domain containing 12
  • Vertebrate Orthologs
    10
  • Human Ortholog
    THAP12, THAP domain containing 12
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DAP4, P52rIPK, PRKRIR, THAP0
  • Links
    NCBI Gene ID: 5612
    neXtProt AC: NX_O43422
    UniProt: O43422

  • Chr Location
    11q13.5; chr11:76349956-76380965 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 37952
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: THAP12
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 72981 NCBI Gene Model | MGI Sequence Detail 14935 C57BL/6J ±  kb
transcript NM_001355114 RefSeq | MGI Sequence Detail 3674 C57BL/6  
polypeptide Q9CUX1 UniProt | EBI | MGI Sequence Detail 758 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 93
    cDNA 92
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 14
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory